Jelle Hendrix
Overview
Explore the profile of Jelle Hendrix including associated specialties, affiliations and a list of published articles.
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Articles
59
Citations
1500
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Recent Articles
1.
Belousov A, Maslov I, Orekhov P, Khorn P, Kuzmichev P, Baleeva N, et al.
iScience
. 2024 Aug;
27(8):110466.
PMID: 39156645
Solvatochromic compounds have emerged as valuable environment-sensitive probes for biological research. Here we used thiol-reactive solvatochromic analogs of the green fluorescent protein (GFP) chromophore to track conformational changes in two...
2.
Dilissen S, Silva P, Smolentseva A, Kache T, Thoelen R, Hendrix J
Biochim Biophys Acta Gen Subj
. 2024 Jul;
1868(9):130673.
PMID: 39029539
Background: Biomolecular condensation via liquid-liquid phase separation (LLPS) is crucial for orchestrating cellular activities temporospatially. Although the rheological heterogeneity of biocondensates and the structural dynamics of their constituents carry critical...
3.
Pancaro A, Szymonik M, Perez Schmidt P, Erol G, Garcia Barrientos A, Polito L, et al.
ACS Appl Mater Interfaces
. 2024 May;
16(23):30556-30566.
PMID: 38806166
Mannose-binding lectin (MBL) activates the complement system lectin pathway and subsequent inflammatory mechanisms. The incidence and outcome of many human diseases, such as brain ischemia and infections, are associated with...
4.
Luginina A, Maslov I, Khorn P, Volkov O, Khnykin A, Kuzmichev P, et al.
J Mol Biol
. 2023 Oct;
435(23):168310.
PMID: 37806553
G protein-coupled receptors (GPCRs) form the largest superfamily of membrane proteins in the human genome, and represent one of the most important classes of drug targets. Their structural studies facilitate...
5.
Coucke Q, Parveen N, Fernandez G, Qian C, Hofkens J, Debyser Z, et al.
Biophys Rep (N Y)
. 2023 Aug;
3(3):100122.
PMID: 37649577
Fluorescence lifetime imaging microscopy (FLIM) is a popular modality to create additional contrast in fluorescence images. By carefully analyzing pixel-based nanosecond lifetime patterns, FLIM allows studying complex molecular populations. At...
6.
Sub-millisecond conformational dynamics of the A adenosine receptor revealed by single-molecule FRET
Maslov I, Volkov O, Khorn P, Orekhov P, Gusach A, Kuzmichev P, et al.
Commun Biol
. 2023 Apr;
6(1):362.
PMID: 37012383
The complex pharmacology of G-protein-coupled receptors (GPCRs) is defined by their multi-state conformational dynamics. Single-molecule Förster Resonance Energy Transfer (smFRET) is well suited to quantify dynamics for individual protein molecules;...
7.
Agam G, Gebhardt C, Popara M, Machtel R, Folz J, Ambrose B, et al.
Nat Methods
. 2023 Mar;
20(4):523-535.
PMID: 36973549
Single-molecule Förster-resonance energy transfer (smFRET) experiments allow the study of biomolecular structure and dynamics in vitro and in vivo. We performed an international blind study involving 19 laboratories to assess...
8.
Maslov I, Hendrix J
Elife
. 2022 Oct;
11.
PMID: 36260068
Single-molecule fluorescence spectroscopy and molecular dynamics simulations illuminate the structure and dynamics of PSD-95, a protein involved in neural plasticity.
9.
Lemmens V, Thevelein B, Vella Y, Kankowski S, Leonhard J, Mizuno H, et al.
Cell Mol Life Sci
. 2022 Oct;
79(11):540.
PMID: 36197517
Glycine receptors (GlyRs) are ligand-gated pentameric chloride channels in the central nervous system. GlyR-α3 is a possible target for chronic pain treatment and temporal lobe epilepsy. Alternative splicing into K...
10.
Solis-Fernandez G, Montero-Calle A, Sanchez-Martinez M, Pelaez-Garcia A, Fernandez-Acenero M, Pallares P, et al.
Br J Cancer
. 2022 Mar;
126(11):1604-1615.
PMID: 35347323
Background: Liver metastasis is the primary cause of colorectal cancer (CRC)-associated death. Aryl-hydrocarbon receptor-interacting protein (AIP), a putative positive intermediary in aryl-hydrocarbon receptor-mediated signalling, is overexpressed in highly metastatic human...