Jeliazko R Jeliazkov
Overview
Explore the profile of Jeliazko R Jeliazkov including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
22
Citations
1521
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Chinery L, Jeliazkov J, Deane C
MAbs
. 2024 Nov;
16(1):2434121.
PMID: 39611407
Antibodies are a popular and powerful class of therapeutic due to their ability to exhibit high affinity and specificity to target proteins. However, the majority of antibody therapeutics are not...
2.
Stark Y, Menard F, Jeliazkov J, Ernst P, Chembath A, Ashraf M, et al.
Proc Natl Acad Sci U S A
. 2024 Jun;
121(27):e2318198121.
PMID: 38917007
Establishing modular binders as diagnostic detection agents represents a cost- and time-efficient alternative to the commonly used binders that are generated one molecule at a time. In contrast to these...
3.
Alford R, Leaver-Fay A, Jeliazkov J, OMeara M, DiMaio F, Park H, et al.
J Chem Theory Comput
. 2022 Jun;
18(7):4594.
PMID: 35667008
No abstract available.
4.
Krivacic C, Kundert K, Pan X, Pache R, Liu L, Conchuir S, et al.
Proc Natl Acad Sci U S A
. 2022 Mar;
119(11):e2115480119.
PMID: 35254891
SignificanceComputational protein design promises to advance applications in medicine and biotechnology by creating proteins with many new and useful functions. However, new functions require the design of specific and often...
5.
Dempsey D, Viennet T, Iwase R, Park E, Henriquez S, Chen Z, et al.
Nat Struct Mol Biol
. 2021 Oct;
28(10):858-868.
PMID: 34625746
Phosphatase and tensin homolog (PTEN) is a phosphatidylinositol-3,4,5-triphosphate (PIP) phospholipid phosphatase that is commonly mutated or silenced in cancer. PTEN's catalytic activity, cellular membrane localization and stability are orchestrated by...
6.
Frick R, Hoydahl L, Petersen J, du Pre M, Kumari S, Berntsen G, et al.
Sci Immunol
. 2021 Aug;
6(62).
PMID: 34417258
Antibodies specific for peptides bound to human leukocyte antigen (HLA) molecules are valuable tools for studies of antigen presentation and may have therapeutic potential. Here, we generated human T cell...
7.
Waltenspuhl Y, Jeliazkov J, Kummer L, Pluckthun A
Sci Rep
. 2021 Apr;
11(1):8630.
PMID: 33883583
Membrane proteins such as G protein-coupled receptors (GPCRs) carry out many fundamental biological functions, are involved in a large number of physiological responses, and are thus important drug targets. To...
8.
Jeliazkov J, Frick R, Zhou J, Gray J
PLoS One
. 2021 Mar;
16(3):e0234282.
PMID: 33764990
In recent years, the observed antibody sequence space has grown exponentially due to advances in high-throughput sequencing of immune receptors. The rise in sequences has not been mirrored by a...
9.
Akbar R, Robert P, Pavlovic M, Jeliazkov J, Snapkov I, Slabodkin A, et al.
Cell Rep
. 2021 Mar;
34(11):108856.
PMID: 33730590
Antibody-antigen binding relies on the specific interaction of amino acids at the paratope-epitope interface. The predictability of antibody-antigen binding is a prerequisite for de novo antibody and (neo-)epitope design. A...
10.
Guest J, Vreven T, Zhou J, Moal I, Jeliazkov J, Gray J, et al.
Structure
. 2021 Feb;
29(6):606-621.e5.
PMID: 33539768
Accurate predictive modeling of antibody-antigen complex structures and structure-based antibody design remain major challenges in computational biology, with implications for biotherapeutics, immunity, and vaccines. Through a systematic search for high-resolution...