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Jeffrey Rosenfeld

Explore the profile of Jeffrey Rosenfeld including associated specialties, affiliations and a list of published articles. Areas
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Articles 52
Citations 1986
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Recent Articles
1.
Berry J, Maragakis N, Macklin E, Chibnik L, Quintana M, Saville B, et al.
JAMA . 2025 Mar; PMID: 40067821
Importance: Bioenergetic failure has been proposed as a driver of amyotrophic lateral sclerosis (ALS). CNM-Au8 is a suspension of gold nanocrystals that catalyzes the conversion of nicotinamide adenine dinucleotide hydride...
2.
Shefner J, Oskarsson B, Macklin E, Chibnik L, Quintana M, Saville B, et al.
JAMA . 2025 Mar; PMID: 40067755
Importance: Amyotrophic lateral sclerosis (ALS) is a fatal disease. The sigma-1 (σ1) receptor emerged as a target for intervention. Objective: To determine the effects of pridopidine, a σ1-receptor agonist, in...
3.
Andrews J, Paganoni S, Macklin E, Chibnik L, Quintana M, Saville B, et al.
JAMA Neurol . 2025 Mar; PMID: 40067754
Importance: Myeloperoxidase is one of the most abundant peroxidase enzymes in activated myeloid cells. Myeloperoxidase inhibitors may have a clinical benefit in amyotrophic lateral sclerosis (ALS) by slowing neurodegeneration via...
4.
Paganoni S, Fournier C, Macklin E, Chibnik L, Quintana M, Saville B, et al.
JAMA Netw Open . 2025 Feb; 8(2):e2459058. PMID: 39960672
Importance: The etiology of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease, is unknown. However, neuroinflammation and complement activation may play a role in disease progression. Objective: To determine the...
5.
Stenson K, Chew S, Dong S, Heithoff K, Wang M, Rosenfeld J
J Manag Care Spec Pharm . 2024 Oct; 30(11):1239-1247. PMID: 39471269
Background: People living with ALS (plwALS) experience motor control loss, speech/swallowing difficulties, respiratory insufficiency, and early death. Advancing disease stage is typically associated with a greater burden on the health...
6.
Jamall S, Baker N, Peterson G, Tsao B, Rosenfeld J
J Clin Neuromuscul Dis . 2023 Nov; 25(2):59-62. PMID: 37962191
Objectives: Anti-neurofascin-155 IgG4 (NF-155) antibody disease has previously been associated with a subset of patients with chronic inflammatory demyelinating polyradiculoneuropathy. We report a case of NF-155 positive polyneuropathy that initially...
7.
Linares G, Li Y, Chang W, Rubin-Sigler J, Mendonca S, Hong S, et al.
Cell Stem Cell . 2023 Feb; 30(2):171-187.e14. PMID: 36736291
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease caused by many diverse genetic etiologies. Although therapeutics that specifically target causal mutations may rescue individual types of ALS, such approaches...
8.
Nagaya N, Rosenfeld J, Lee G, Kim I
Prostate Int . 2021 Oct; 9(3):125-131. PMID: 34692584
Background: Prostate cancer in African American (AA) men has a poor prognosis. This study aimed to identify potential genetic risk factors for prostate cancer in AA men. Methods: We used...
9.
Kweh B, Rosenfeld J, Hunn M, Tee J
World Neurosurg . 2020 Sep; 145:229-240. PMID: 32949795
Background: The survival outcomes of clear cell ependymomas are poorly understood. This study clarifies the role of surgery and adjuvant therapy when this morphologically distinct tumor is encountered. Methods: A...
10.
Kweh B, Lee H, Tan T, ODonohoe T, Mathew J, Fitzgerald M, et al.
Global Spine J . 2020 Sep; 11(4):525-532. PMID: 32875892
Study Design: This was an ambispective clinical quality registry study. Objective: To evaluate utility of 11-variable modified Frailty Index (mFI) in predicting postoperative outcomes among patients ≥80 years undergoing spinal...