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Jeffrey Pido-Lopez

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Articles 18
Citations 277
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Recent Articles
1.
Pido-Lopez J, Tanudjojo B, Farag S, Bondulich M, Andre R, Tabrizi S, et al.
Sci Rep . 2019 May; 9(1):7202. PMID: 31076648
Huntington's disease (HD) is an inherited neurodegenerative disorder caused by the expansion of the CAG repeat in exon 1 of the huntingtin (HTT) gene, which results in a mutant protein...
2.
Pido-Lopez J, Andre R, Benjamin A, Ali N, Farag S, Tabrizi S, et al.
Sci Rep . 2018 Aug; 8(1):11447. PMID: 30061661
Neurodegenerative diseases, characterised by the progressive and selective neuronal death in the central nervous system, are frequently accompanied by an activated immune system. In Huntington's disease (HD), clinical and animal...
3.
Girdlestone J, Pido-Lopez J, Srivastava S, Chai J, Leaver N, Galleu A, et al.
Cytotherapy . 2015 Aug; 17(9):1188-99. PMID: 26276002
Background Aims: Multipotent mesenchymal stromal cells (MSCs) are distinguished by their ability to differentiate into a number of stromal derivatives of interest for regenerative medicine, but they also have immunoregulatory...
4.
Pido-Lopez J, Kwok W, Mitchell T, Heyderman R, Williams N
PLoS Pathog . 2011 Dec; 7(12):e1002396. PMID: 22144893
The upper respiratory tract mucosa is the location for commensal Streptococcus (S.) pneumoniae colonization and therefore represents a major site of contact between host and bacteria. The CD4(+) T cell...
5.
Bergmeier L, Babaahmady K, Pido-Lopez J, Heesom K, Kelly C, Lehner T
Immunology . 2009 Dec; 129(4):506-15. PMID: 20002211
This study is based on the evidence that immunization of macaques with human CD4(+) T cells elicits prevention of simian immunodeficiency virus (SIV) infection. We hypothesized that heat-shock protein 70...
6.
Pido-Lopez J, Jeffrey P, Wang Y, Seidl T, Babaahmady K, Vaughan R, et al.
Eur J Immunol . 2009 Jul; 39(7):1956-65. PMID: 19585516
Allogeneic immunity is one of the most potent natural immune responses. APOBEC3G (A3G) is an intracellular anti-viral factor that deaminates cytidine to uridine. Allogeneic stimulation of human CD4(+) T cells...
7.
Westrop S, Qazi N, Pido-Lopez J, Nelson M, Gazzard B, Gotch F, et al.
PLoS One . 2009 May; 4(5):e5474. PMID: 19434236
Background: HIV-1(+) individuals who, without therapy, conserve cellular anti-HIV-1 responses, present with high, stable CD4(+) T-cell numbers, and control viral replication, facilitate analysis of atypical viro-immunopathology. In the absence of...
8.
Aspinall R, Pido-Lopez J, Imami N, Henson S, Ngom P, Morre M, et al.
Rejuvenation Res . 2007 Mar; 10(1):5-17. PMID: 17378748
Old age is accompanied by an increased incidence of infection and poorer responses to vaccination. In this proof of principle study, old female rhesus macaques (aged 18.5 to 23.9 years)...
9.
Pido-Lopez J, Whittall T, Wang Y, Bergmeier L, Babaahmady K, Singh M, et al.
J Immunol . 2007 Jan; 178(3):1671-9. PMID: 17237417
Apolipoprotein B mRNA-editing, enzyme-catalytic, polypeptide-like-3G (A3G) is an intracellular innate antiviral factor that deaminates retroviral cytidine to uridine. In an attempt to harness the anti-HIV effect of A3G, we searched...
10.
Ngom P, Collinson A, Pido-Lopez J, Henson S, Prentice A, Aspinall R
Am J Clin Nutr . 2004 Aug; 80(3):722-8. PMID: 15321814
Background: In rural Gambians, the season of birth strongly predicts adult mortality. Those born during the harvest season have longer life spans than do those born during the hungry season,...