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Jeffrey D Rudolf

Explore the profile of Jeffrey D Rudolf including associated specialties, affiliations and a list of published articles. Areas
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Articles 64
Citations 961
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Recent Articles
1.
McCadden C, Alsup T, Ghiviriga I, Rudolf J
J Ind Microbiol Biotechnol . 2025 Jan; 52. PMID: 39880799
One-sentence Summary: Genome-guided biotransformation of the bioactive diterpenoid abietic acid in Streptomyces yielded seven oxidized derivatives including four that have not been previously seen from bacteria.
2.
Chen X, Urban J, Wurlitzer J, Wei X, Han J, OConnor S, et al.
Proc Natl Acad Sci U S A . 2024 Dec; 121(51):e2413007121. PMID: 39671179
Insects employ terpenoids for communication both within and between species. While terpene synthases derived from isoprenyl diphosphate synthase have been shown to catalyze terpenoid biosynthesis in some insects, canonical terpene...
3.
Wang Z, Alsup T, Pan X, Li L, Tian J, Yang Z, et al.
Chem Sci . 2024 Nov; 16(1):310-317. PMID: 39611033
Meroterpenoids are hybrid natural products that arise from the integration of terpenoid and non-terpenoid biosynthetic pathways. While the biosynthesis of fungal meroterpenoids typically follows a well-established sequence of prenylation, epoxidation,...
4.
Rudolf J, Barra L, Awakawa T
Beilstein J Org Chem . 2024 Nov; 20:2720-2721. PMID: 39498450
No abstract available.
5.
Alsup T, Li Z, McCadden C, Jagels A, Lomowska-Keehner D, Marshall E, et al.
RSC Chem Biol . 2024 Aug; PMID: 39144403
The chemical logic associated with assembly of many bacterial terpenoids remains poorly understood. We focused our efforts on the early-stage biosynthesis of the phenalinolactone diterpenoids, demonstrating that the -perhydrophenanthrene core...
6.
Mandelare P, Yee S, Icenhour D, Kaweesa E, McCauley M, Risinger A, et al.
Chembiochem . 2024 Jul; 25(20):e202400398. PMID: 39030818
Marine-derived fungi have emerged as a source for novel metabolites with a broad range of bioactivities. However, accessing the full potential of fungi under standard laboratory conditions remains challenging. LC-MS-based...
7.
Alsup T, Opoku M, Rudolf J
Methods Enzymol . 2024 Jun; 699:395-417. PMID: 38942512
Expression and purification of membrane-bound proteins remains a challenge and limits enzymology efforts, contributing to a substantial knowledge gap in the biochemical functions of many proteins found in nature. Accordingly,...
8.
Li Z, Jindani S, Kojasoy V, Ortega T, Marshall E, Abboud K, et al.
Beilstein J Org Chem . 2024 Jun; 20:1320-1326. PMID: 38887579
Eunicellane diterpenoids are a unique family of natural products containing a foundational 6/10-bicyclic framework and can be divided into two main classes, and , based on the configurations of their...
9.
Rudolf J, Loesgen S
ACS Cent Sci . 2024 Apr; 10(3):511-513. PMID: 38559289
No abstract available.
10.
Fluegel L, Deng M, Su P, Kalkreuter E, Yang D, Rudolf J, et al.
J Ind Microbiol Biotechnol . 2024 Jan; 51. PMID: 38262768
One-sentence Summary: Implementation of a CRISPR-Cas9 system in Streptomyces platensis CB00739 enabled the construction of a suite of designer recombinant strains for the overproduction of platensimycin, platencin, and platensilin, discovery...