Jeffrey D Klopfenstein
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Explore the profile of Jeffrey D Klopfenstein including associated specialties, affiliations and a list of published articles.
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65
Citations
948
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Recent Articles
11.
Nalamolu K, Challa S, Fornal C, Grudzien N, Jorgenson L, Choudry M, et al.
Transl Stroke Res
. 2021 Jan;
12(5):923-936.
PMID: 33426628
The intense inflammatory response triggered in the brain after focal cerebral ischemia is detrimental. Recently, we showed that the suppression of toll-like receptors (TLRs) 2 and 4 attenuates infarct size...
12.
Nalamolu K, Venkatesh I, Mohandass A, Klopfenstein J, Pinson D, Wang D, et al.
Neuromolecular Med
. 2019 May;
21(4):529-539.
PMID: 31077035
Emerging stroke literature suggests that treatment of experimentally induced stroke with stem cells offered post-stroke neuroprotection via exosomes produced by these cells. Treatment with exosomes has great potential to overcome...
13.
Nalamolu K, Venkatesh I, Mohandass A, Klopfenstein J, Pinson D, Wang D, et al.
Cell Physiol Biochem
. 2019 Apr;
52(6):1280-1291.
PMID: 31026391
Background/aims: Recent studies demonstrated that the treatment with mesenchymal stem cells (MSCs) obtained from the human umbilical cord blood improved survival, reduced brain damage, prevented apoptosis, suppressed inflammatory responses, downregulated...
14.
Nalamolu K, Chelluboina B, Magruder I, Fru D, Mohandass A, Venkatesh I, et al.
Stroke Vasc Neurol
. 2018 Oct;
3(3):153-159.
PMID: 30294471
Background And Purpose: Recent reports from our laboratory demonstrated the post-ischaemic expression profile of various matrix metalloproteinases (MMPs) in rats and the detrimental role of MMP-12 in post-stroke brain damage....
15.
Yoo A, Jou J, Klopfenstein J, Kattah J
Front Neurol
. 2018 Jun;
9:358.
PMID: 29892257
Background: Infratentorial siderosis (iSS) is a progressive degenerative disorder targeting primarily the cerebellum and cranial nerve eighth; therefore, progressive ataxia and its neuro-otological findings are common. Toxicity from hemosiderin involves...
16.
Nalamolu K, Smith N, Chelluboina B, Klopfenstein J, Pinson D, Wang D, et al.
Neuroscience
. 2018 Jun;
384:429.
PMID: 29879419
No abstract available.
17.
Nalamolu K, Smith N, Chelluboina B, Klopfenstein J, Pinson D, Wang D, et al.
Neuroscience
. 2018 Jan;
373:82-91.
PMID: 29337240
Toll-like receptor 2 (TLR2) and TLR4 belong to a family of highly conserved pattern recognition receptors and are well-known upstream sensors of signaling pathways of innate immunity. TLR2 and TLR4...
18.
Chelluboina B, Nalamolu K, Mendez G, Klopfenstein J, Pinson D, Wang D, et al.
Cell Physiol Biochem
. 2017 Nov;
44(4):1360-1369.
PMID: 29186705
Background/aims: Stem cell treatment is one of the potential treatment options for ischemic stroke. We recently demonstrated a protective effect of human umbilical cord blood-derived mesenchymal stem cells (HUCB-MSCs) in...
19.
Chelluboina B, Nalamolu K, Klopfenstein J, Pinson D, Wang D, Vemuganti R, et al.
Mol Neurobiol
. 2017 Feb;
55(2):1405-1409.
PMID: 28155200
The role of matrix metalloproteinase-12 (MMP-12) in the pathogenesis of several inflammatory diseases such as chronic obstructive pulmonary disease, emphysema, and asthma is well established. Several new studies and recent...
20.
Chelluboina B, Klopfenstein J, Pinson D, Wang D, Vemuganti R, Veeravalli K
Stroke
. 2015 Nov;
46(12):3523-31.
PMID: 26534974
Background And Purpose: Matrix metalloproteinases (MMPs) have a central role in compromising the integrity of the blood-brain barrier (BBB). The role of MMP-12 in brain damage after ischemic stroke remains...