Jeffrey C Wolchok
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Explore the profile of Jeffrey C Wolchok including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
205
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Recent Articles
1.
Reed C, Huynh T, Schluns J, Phelps P, Hestekin J, Wolchok J
Tissue Eng Part A
. 2023 Sep;
30(5-6):181-191.
PMID: 37658842
There are currently no surgical procedures that effectively address the treatment of volumetric muscle loss (VML) injuries that has motivated the development of implantable scaffolding. In this study, the effectiveness...
2.
Roberts K, Kim J, Huynh T, Schluns J, Dunlap G, Hestekin J, et al.
BMC Musculoskelet Disord
. 2023 Apr;
24(1):321.
PMID: 37095469
Volumetric muscle loss overwhelms skeletal muscle's ordinarily capable regenerative machinery, resulting in severe functional deficits that have defied clinical repair strategies. In this manuscript we pair the early in vivo...
3.
Washington T, Wolchok J
J Physiol
. 2023 Feb;
601(7):1157-1158.
PMID: 36799356
No abstract available.
4.
Dunn C, Ferreira L, Venier S, Ali S, Wolchok J, Balachandran K
Neurotrauma Rep
. 2022 Aug;
3(1):224-239.
PMID: 35919509
The pathological effects of repeated traumatic brain injuries (TBIs) are largely unknown. To gain a detailed understanding of the cortical tissue acute biological response after one or two TBIs, we...
5.
Kim J, Roberts K, Dunlap G, Perry R, Washington T, Wolchok J
J Tissue Eng Regen Med
. 2022 Feb;
16(4):367-379.
PMID: 35113494
Aging hinders the effectiveness of regenerative medicine strategies targeting the repair of volumetric muscle loss (VML) injury. Anabolic steroids have been shown to improve several factors which contribute to the...
6.
Washington T, Perry Jr R, Kim J, Haynie W, Greene N, Wolchok J
Exp Physiol
. 2021 Feb;
106(4):994-1004.
PMID: 33600045
New Findings: What is the central question of this study? Following large traumatic loss of muscle tissue (volumetric muscle loss; VML), permanent functional and cosmetic deficits present themselves and regenerative...
7.
Brown L, Perry Jr R, Haynie W, Lee D, Rosa-Caldwell M, Brown J, et al.
Mech Ageing Dev
. 2020 Nov;
194:111404.
PMID: 33249192
The purpose of this study was to determine whether sarcopenic obesity accelerates impairments in muscle maintenance through the investigation of cell cycle progression and myogenic, inflammatory, catabolic and protein synthetic...
8.
Huynh T, Kim J, Dunlap G, Ahmadi S, Wolchok J
J Shoulder Elbow Surg
. 2020 Jul;
29(12):e478-e490.
PMID: 32713662
Introduction: Extracellular matrix (ECM) gels have shown efficacy for the treatment of damaged tissues, most notably cardiac muscle. We hypothesized that the ECM gel prepared from skeletal muscle could be...
9.
Kim J, Kasukonis B, Dunlap G, Perry R, Washington T, Wolchok J
Tissue Eng Part A
. 2019 May;
26(1-2):3-14.
PMID: 31064280
In this study, the influence of age on effectiveness of regenerative repair for the treatment of volumetric muscle loss (VML) injury was explored. Tibialis anterior (TA) VML injuries were repaired...
10.
Roberts K, Kim J, White S, Hestekin J, Wolchok J
J Vis Exp
. 2019 Feb;
(144).
PMID: 30774136
Engineered scaffolds derived from extracellular matrix (ECM) have driven significant interest in medicine for their potential in expediting wound closure and healing. Extraction of extracellular matrix from fibrogenic cell cultures...