Jeffrey A Sorelle
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Explore the profile of Jeffrey A Sorelle including associated specialties, affiliations and a list of published articles.
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47
Citations
498
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Recent Articles
1.
Thummala A, Sudhakaran R, Gurram A, Mersch J, Badalamenti A, Gottaway G, et al.
Genet Med Open
. 2024 Dec;
2:101867.
PMID: 39669626
Purpose: A primary challenge in clinical genetics is accurate interpretation of identified variants and relaying the information to patients and providers. Inconsistencies around handling variant reclassifications and notifying patients, combined...
2.
von Itzstein M, Liu J, Mu-Mosley H, Fattah F, Park J, Sorelle J, et al.
JTO Clin Res Rep
. 2024 Dec;
6(1):100751.
PMID: 39619775
Introduction: Racial and ethnic disparities in the presentation and outcomes of lung cancer are widely known. To evaluate potential factors contributing to these observations, we measured systemic immune parameters in...
3.
Bishop J, Nakaguro M, Weinreb I, Palsgrove D, Rooper L, Vandergriff T, et al.
Head Neck Pathol
. 2024 Oct;
18(1):106.
PMID: 39417927
Squamous cell carcinoma (SCC) is one of the most common malignancies involving the parotid gland, but it has been recognized that the vast majority of parotid SCC represents metastases, especially...
4.
Zhong X, Moresco J, Sorelle J, Song R, Jiang Y, Nguyen M, et al.
Proc Natl Acad Sci U S A
. 2024 Jul;
121(31):e2409232121.
PMID: 39047044
Despite the availability of life-extending treatments for B cell leukemias and lymphomas, many of these cancers remain incurable. Thus, the development of new molecular targets and therapeutics is needed to...
5.
von Itzstein M, Liu J, Mu-Mosley H, Fattah F, Park J, Sorelle J, et al.
bioRxiv
. 2024 Jun;
PMID: 38915535
Introduction: Racial and ethnic disparities in the presentation and outcomes of lung cancer are widely known. To evaluate potential factors contributing to these observations, we measured systemic immune parameters in...
6.
Sorelle J, Funke B, Eno C, Ji J, Santani A, Bayrak-Toydemir P, et al.
J Mol Diagn
. 2023 Dec;
26(3):159-167.
PMID: 38103592
As the number of genes associated with various germline disorders continues to grow, it is becoming more difficult for clinical laboratories to maintain separate assays for interrogating disease-focused gene panels....
7.
Zhong X, Moresco J, Diedrich J, Pinto A, Sorelle J, Wang J, et al.
Proc Natl Acad Sci U S A
. 2023 Dec;
120(50):e2314429120.
PMID: 38055739
We detected ENU-induced alleles of (encoding the major facilitator superfamily domain containing 1 protein) that caused lymphopenia, splenomegaly, progressive liver pathology, and extramedullary hematopoiesis (EMH). MFSD1 is a lysosomal membrane-bound...
8.
Zhong X, Peddada N, Wang J, Moresco J, Zhan X, Shelton J, et al.
Nat Commun
. 2023 Nov;
14(1):7786.
PMID: 38012144
Distinct pathways and molecules may support embryonic versus postnatal thymic epithelial cell (TEC) development and maintenance. Here, we identify a mechanism by which TEC numbers and function are maintained postnatally....
9.
Song R, McAlpine W, Fond A, Nair-Gill E, Choi J, Nystrom E, et al.
Nat Commun
. 2023 Jun;
14(1):3652.
PMID: 37339972
A key feature in intestinal immunity is the dynamic intestinal barrier, which separates the host from resident and pathogenic microbiota through a mucus gel impregnated with antimicrobial peptides. Using a...
10.
Aguilar M, Chen H, Sahoo S, Zheng W, Grubman J, Sorelle J, et al.
Am J Surg Pathol
. 2023 Mar;
47(5):618-629.
PMID: 36939046
Despite refinements in histologic criteria for the diagnosis of endometrioid precancers, many challenging cases are encountered in daily practice, creating diagnostic uncertainty and suboptimal patient management. Recently, an immunohistochemical 3-marker...