Jeffery P Struewing
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Explore the profile of Jeffery P Struewing including associated specialties, affiliations and a list of published articles.
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46
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2808
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Recent Articles
11.
Sigurdson A, Land C, Bhatti P, Pineda M, Brenner A, Carr Z, et al.
Radiat Res
. 2009 Jan;
171(1):77-88.
PMID: 19138047
Risk factors for thyroid cancer remain largely unknown except for ionizing radiation exposure during childhood and a history of benign thyroid nodules. Because thyroid nodules are more common than thyroid...
12.
Bhatti P, Doody M, Alexander B, Yuenger J, Simon S, Weinstock R, et al.
Cancer Epidemiol Biomarkers Prev
. 2008 Aug;
17(8):2007-11.
PMID: 18708391
Genome-wide association studies are discovering relationships between single-nucleotide polymorphisms and breast cancer, but the functions of these single-nucleotide polymorphisms are unknown and environmental exposures are likely to be important. We...
13.
Olshen A, Gold B, Lohmueller K, Struewing J, Satagopan J, Stefanov S, et al.
BMC Genet
. 2008 Feb;
9:14.
PMID: 18251999
Background: Genetic isolates such as the Ashkenazi Jews (AJ) potentially offer advantages in mapping novel loci in whole genome disease association studies. To analyze patterns of genetic variation in AJ,...
14.
Chodick G, Struewing J, Ron E, Rutter J, Iscovich J
Eur J Med Genet
. 2007 Dec;
51(2):141-7.
PMID: 18158280
To evaluate the potential contribution of mutations in the BRCA1 and BRCA2 genes to male breast cancer (MBC), we expanded a previous study to screen a total of 261 Israeli...
15.
Antoniou A, Sinilnikova O, Simard J, Leone M, Dumont M, Neuhausen S, et al.
Am J Hum Genet
. 2007 Nov;
81(6):1186-200.
PMID: 17999359
RAD51 is an important component of double-stranded DNA-repair mechanisms that interacts with both BRCA1 and BRCA2. A single-nucleotide polymorphism (SNP) in the 5' untranslated region (UTR) of RAD51, 135G-->C, has...
16.
Pereira L, Pineda M, Rowe W, Fonseca L, Greene M, Offit K, et al.
BMC Genet
. 2007 Oct;
8:68.
PMID: 17916242
Background: We studied linkage disequilibrium (LD) patterns at the BRCA1 locus, a susceptibility gene for breast and ovarian cancer, using a dense set of 114 single nucleotide polymorphisms in 5...
17.
Bhatti P, Struewing J, Alexander B, Hauptmann M, Bowen L, Mateus-Pereira L, et al.
Int J Cancer
. 2007 Sep;
122(1):177-82.
PMID: 17764108
High-dose ionizing radiation exposure to the breast and rare autosomal dominant genes have been linked with increased breast cancer risk, but the role of low-to-moderate doses from protracted radiation exposure...
18.
Couch F, Sinilnikova O, Vierkant R, Pankratz V, Fredericksen Z, Stoppa-Lyonnet D, et al.
Cancer Epidemiol Biomarkers Prev
. 2007 Jul;
16(7):1416-21.
PMID: 17627006
The AURKA oncogene is associated with abnormal chromosome segregation and aneuploidy and predisposition to cancer. Amplification of AURKA has been detected at higher frequency in tumors from BRCA1 and BRCA2...
19.
Easton D, Pooley K, Dunning A, Pharoah P, Thompson D, Ballinger D, et al.
Nature
. 2007 May;
447(7148):1087-93.
PMID: 17529967
Breast cancer exhibits familial aggregation, consistent with variation in genetic susceptibility to the disease. Known susceptibility genes account for less than 25% of the familial risk of breast cancer, and...
20.
Zhang J, Finney R, Rowe W, Edmonson M, Yang S, Dracheva T, et al.
Genome Res
. 2007 May;
17(7):1111-7.
PMID: 17525135
Systematic investigations of genetic changes in tumors are expected to lead to greatly improved understanding of cancer etiology. To meet the analytical challenges presented by such studies, we developed the...