Jeanne N Hansen
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Explore the profile of Jeanne N Hansen including associated specialties, affiliations and a list of published articles.
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11
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102
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Recent Articles
1.
Sahasrabudhe D, Liesveld J, Minhajuddin M, Singh N, Nath S, Kumar V, et al.
Sci Rep
. 2024 Jun;
14(1):12868.
PMID: 38834690
Acute myeloid leukemia (AML) is fatal in the majority of adults. Identification of new therapeutic targets and their pharmacologic modulators are needed to improve outcomes. Previous studies had shown that...
2.
Khazan N, Quarato E, Singh N, Snyder C, Moore T, Miller J, et al.
Cancers (Basel)
. 2023 Jul;
15(13).
PMID: 37444542
Small-molecule inhibitors of PD-L1 are postulated to control immune evasion in tumors similar to antibodies that target the PD-L1/PD-1 immune checkpoint axis. However, the identity of targetable PD-L1 inducers is...
3.
Khazan N, Kim K, Hansen J, Singh N, Moore T, Snyder C, et al.
J Med Chem
. 2022 Apr;
65(8):6039-6055.
PMID: 35404047
Vitamin-D receptor (VDR) mRNA is overexpressed in neuroblastoma and carcinomas of lung, pancreas, and ovaries and predicts poor prognoses. VDR antagonists may be able to inhibit tumors that overexpress VDR....
4.
Hua Z, Hansen J, He M, Dai S, Choi Y, Fulton M, et al.
Oncogenesis
. 2020 May;
9(5):50.
PMID: 32415090
Aberrant expression of protein arginine methyltransferases (PRMTs) has been implicated in a number of cancers, making PRMTs potential therapeutic targets. But it remains not well understood how PRMTs impact specific...
5.
Doms A, Sanabria T, Hansen J, Altan-Bonnet N, Holm G
J Virol
. 2018 Jun;
92(18).
PMID: 29950420
Following the initial detection of viral infection, innate immune responses trigger the induction of numerous interferon-stimulated genes (ISGs) to inhibit virus replication and dissemination. One such ISG encodes cholesterol-25-hydroxylase (CH25H),...
6.
Hansen J, Li X, Zheng Y, Lotta Jr L, Dedhe A, Schor N
ACS Chem Neurosci
. 2017 Aug;
8(10):2118-2123.
PMID: 28800395
Neuroblastoma is a cancer of the neural crest almost exclusively seen in childhood. While children with single, small primary tumors are often cured with surgery alone, the 65% of children...
7.
Hansen J, Lotta Jr L, Eberhardt A, Schor N, Li X
J Cancer Res Ther (Manch)
. 2017 Jul;
4(2):11-18.
PMID: 28713571
Neuroblastoma, the most frequently occurring extracranial solid tumor of childhood, arises from neural crest-derived cells that are arrested at an early stage of differentiation in the developing sympathetic nervous system....
8.
Li X, Eberhardt A, Hansen J, Bohmann D, Li H, Schor N
FASEB J
. 2017 Feb;
31(6):2327-2339.
PMID: 28213359
The eyes absent (EYA) family proteins are conserved transcriptional coactivators with intrinsic protein phosphatase activity. They play an essential role in the development of various organs in metazoans. These functions...
9.
Proschel C, Hansen J, Ali A, Tuttle E, Lacagnina M, Buscaglia G, et al.
Eur J Hum Genet
. 2016 Dec;
25(2):216-221.
PMID: 27966542
SIK1 syndrome is a newly described developmental epilepsy disorder caused by heterozygous mutations in the salt-inducible kinase SIK1. To better understand the pathophysiology of SIK1 syndrome, we studied the effects...
10.
Eberhardt A, Hansen J, Koster J, Lotta Jr L, Wang S, Livingstone E, et al.
Oncotarget
. 2016 Aug;
7(39):63629-63639.
PMID: 27571165
Amplification or overexpression of MYCN is associated with poor prognosis of human neuroblastoma. We have recently defined a MYCN-dependent transcriptional signature, including protein arginine methyltransferase 1 (PRMT1), which identifies a...