Jean L Rouleau
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Explore the profile of Jean L Rouleau including associated specialties, affiliations and a list of published articles.
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222
Citations
13772
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Recent Articles
11.
Patel-Murray N, Zhang L, Claggett B, Xu D, Serrano-Fernandez P, Healey M, et al.
J Am Heart Assoc
. 2024 Jun;
13(13):e033544.
PMID: 38904251
Background: Prognostic markers and biological pathways linked to detrimental clinical outcomes in heart failure with preserved ejection fraction (HFpEF) remain incompletely defined. Methods And Results: We measured serum levels of...
12.
Chatur S, Beldhuis I, Claggett B, McCausland F, Neuen B, Desai A, et al.
JACC Heart Fail
. 2024 Jun;
12(10):1692-1703.
PMID: 38842957
Background: Sacubitril/valsartan is a foundational therapy for patients with heart failure. Although current U.S. Food and Drug Administration labeling does not provide guidance regarding initiation or continuation of sacubitril/valsartan in...
13.
Dewan P, Shen L, Ferreira J, Jhund P, Anand I, Chandra A, et al.
Circulation
. 2024 Jun;
150(4):272-282.
PMID: 38841854
Background: A hypothetical concern has been raised that sacubitril/valsartan might cause cognitive impairment because neprilysin is one of several enzymes degrading amyloid-β peptides in the brain, some of which are...
14.
Chatur S, Neuen B, Claggett B, Beldhuis I, Mc Causland F, Desai A, et al.
J Am Coll Cardiol
. 2024 Apr;
83(22):2148-2159.
PMID: 38588927
Background: The Kidney Disease Improving Global Outcomes (KDIGO) classification integrates both estimated glomerular filtration rate and urine-albumin-creatinine ratio to stratify risk more comprehensively in patients with chronic kidney disease. There...
15.
Matsumoto S, Yang M, Shen L, Henderson A, Claggett B, Desai A, et al.
Eur J Heart Fail
. 2024 Apr;
26(5):1125-1138.
PMID: 38587090
Aims: Patients with heart failure (HF) and preserved ejection fraction (HFpEF) have a particularly high prevalence of comorbidities, often necessitating treatment with many medications. The aim of this study was...
16.
Foa A, Vaduganathan M, Claggett B, Pabon M, Lu H, Pfeffer M, et al.
J Am Coll Cardiol
. 2024 Mar;
83(18):1731-1739.
PMID: 38537919
Background: Hypotension is a potential adverse effect of sacubitril/valsartan, but there are limited data regarding the predictors and implications of treatment-related hypotension in heart failure (HF) with mildly reduced and...
17.
Ferreira J, Claggett B, Liu J, Sharma A, Desai A, Anand I, et al.
Int J Cardiol
. 2024 Feb;
402:131818.
PMID: 38307421
Background: Inflammation plays a central role in the genesis and progression of heart failure with preserved ejection fraction (HFpEF). C-reactive protein (CRP) is widely used as means to assess systemic...
18.
Omerovic E, Petrie M, Redfors B, Fremes S, Murphy G, Marquis-Gravel G, et al.
Trials
. 2024 Jan;
25(1):80.
PMID: 38263138
In an era focused on value-based healthcare, the quality of healthcare and resource allocation should be underpinned by empirical evidence. Pragmatic clinical trials (pRCTs) are essential in this endeavor, providing...
19.
Petrie M, Rouleau J, Claggett B, Jering K, van der Meer P, Kober L, et al.
Circulation
. 2024 Jan;
149(4):335-338.
PMID: 38252738
No abstract available.
20.
Tolomeo P, Butt J, Kondo T, Campo G, Desai A, Jhund P, et al.
Eur J Heart Fail
. 2023 Dec;
26(2):245-256.
PMID: 38124454
Aim: Blood urea nitrogen (BUN) to creatinine ratio is associated with worse outcomes in acute heart failure (HF) but little is known about its importance in chronic HF. Methods And...