Jean A Helmijr
Overview
Explore the profile of Jean A Helmijr including associated specialties, affiliations and a list of published articles.
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5
Citations
45
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Recent Articles
1.
Jongbloed E, Jansen M, de Weerd V, Helmijr J, Beaufort C, Reinders M, et al.
Sci Rep
. 2023 Jun;
13(1):10424.
PMID: 37369746
Next generation sequencing of cell-free DNA (cfDNA) is a promising method for treatment monitoring and therapy selection in metastatic breast cancer (MBC). However, distinguishing tumor-specific variants from sequencing artefacts and...
2.
Eyck B, Jansen M, Noordman B, Atmodimedjo P, van der Wilk B, Martens J, et al.
J Pathol
. 2022 Oct;
259(1):35-45.
PMID: 36196486
Active surveillance instead of standard surgery after neoadjuvant chemoradiotherapy (nCRT) has been proposed for patients with oesophageal cancer. Circulating tumour DNA (ctDNA) may be used to facilitate selection of patients...
3.
Vitale S, Helmijr J, Gerritsen M, Coban H, van Dessel L, Beije N, et al.
BMC Cancer
. 2021 Mar;
21(1):315.
PMID: 33761899
Background: Extracellular vesicles (EVs) are actively secreted by cells into body fluids and contain nucleic acids of the cells they originate from. The goal of this study was to detect...
4.
Zhang Y, Wester L, He J, Geiger T, Moerkens M, Siddappa R, et al.
Oncogene
. 2018 Jan;
37(14):1869-1884.
PMID: 29353882
Antiestrogen resistance in estrogen receptor positive (ER) breast cancer is associated with increased expression and activity of insulin-like growth factor 1 receptor (IGF1R). Here, a kinome siRNA screen has identified...
5.
Ramirez-Ardila D, Timmermans A, Helmijr J, Martens J, Berns E, Jansen M
Transl Oncol
. 2017 Sep;
10(5):854-866.
PMID: 28886403
Introduction: While mutations in PIK3CA are most frequently (45%) detected in luminal breast cancer, downstream PI3K/AKT/mTOR pathway activation is predominantly observed in the basal subtype. The aim was to identify...