Jean-Yves Lefrant
Overview
Explore the profile of Jean-Yves Lefrant including associated specialties, affiliations and a list of published articles.
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Articles
169
Citations
5513
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0
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Recent Articles
1.
Santonocito C, Giambra M, Lumia M, Sanfilippo F, Fabbro V, Rubulotta F, et al.
Anaesth Crit Care Pain Med
. 2025 Mar;
:101504.
PMID: 40086731
Introduction: The present study aimed at assessing gender balance in the Editorial roles of Critical Care Medicine (CCM) journals. Methods: A cross-sectional survey was performed for assessing the gender distribution...
2.
Coisy F, Ajavon F, Lipman J, Lefrant J, Bobbia X
Anaesth Crit Care Pain Med
. 2025 Feb;
:101490.
PMID: 39920920
No abstract available.
3.
Roberts J, Sime F, Lipman J, Hernandez-Mitre M, Baptista J, Bruggemann R, et al.
Intensive Care Med
. 2025 Feb;
51(2):302-317.
PMID: 39899034
Purpose: Appropriate antifungal therapy is a major determinant of survival in critically ill patients with invasive fungal disease. We sought to describe whether contemporary dosing of antifungals achieves therapeutic exposures...
4.
Widehem R, Nicolet C, Delannoy V, Barthelemi L, Soulairol I, Lefrant J, et al.
BMJ Open
. 2025 Jan;
15(1):e090396.
PMID: 39832962
Introduction: Intensive care unit (ICU) patients under mechanical ventilation experience mild-to-severe pain. International guidelines emphasise the importance and benefits of multimodal analgesia to minimise opioid consumption and its side effects....
5.
Boulet N, Quenot J, Serrand C, Antier N, Garnier S, Buzancais A, et al.
Crit Care
. 2024 Dec;
28(1):429.
PMID: 39709493
Background: In septic shock, the classic fluid resuscitation strategy can lead to a potentially harmful positive fluid balance. This multicenter, randomized, single-blind, parallel, controlled pilot study assessed the effectiveness of...
6.
Boulet N, Pensier J, Occean B, Peray P, Mimoz O, Rickard C, et al.
Crit Care
. 2024 Nov;
28(1):378.
PMID: 39563416
Background: During central venous catheterization (CVC), ultrasound (US) guidance has been shown to reduce mechanical complications and increase success rates compared to the anatomical landmark (AL) technique. However, the impact...
7.
Simonetti L, Lefrant J, Cireasa B, Poujol H, Leguelinel-Blache G
Eur J Hosp Pharm
. 2024 Sep;
PMID: 39271250
Clinical pharmacy is a fast-growing discipline in Europe, ensuring optimisation and a guarantee of safety in therapeutic management. Within a hospital the intensive care unit (ICU) typically admits the most...
8.
Ceausu D, Boulet N, Roger C, Alonso S, Lefrant J, Boisson C, et al.
Shock
. 2024 Aug;
62(5):682-687.
PMID: 39193888
Introduction: The maximal norepinephrine (NE) dose >1 μg/kg/min during circulatory shock apparently is associated with higher mortality, but this threshold needs confirmation. This study aimed at investigating whether NE infusion...
9.
Coulomb R, Basset P, Mezzarobba M, Masseguin C, Lefrant J, Mura T, et al.
Clin J Sport Med
. 2024 Aug;
PMID: 39158497
Objective: This study assessed the impact of 2 hydration strategies on capillary sodium concentrations during Ultra-Trail du Mont-Blanc (UTMB) 2015. Design: Prospective exposed/nonexposed cohort study. Setting: Ultra-Trail du Mont Blanc...
10.
Kundura L, Cezar R, Ballongue E, Andre S, Michel M, Mettling C, et al.
J Immunol
. 2024 Feb;
212(7):1105-1112.
PMID: 38345346
Genetic defects in the ability to deliver effective perforin have been reported in patients with hemophagocytic lymphohistiocytosis. We tested the hypothesis that a primary perforin deficiency might also be causal...