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Jean-Philippe Perrier

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Articles 7
Citations 80
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Recent Articles
1.
Donnellan E, Perrier J, Keogh K, Stiavnicka M, Collins C, Dunleavy E, et al.
Front Vet Sci . 2022 Oct; 9:993561. PMID: 36277068
Bulls used in artificial insemination, with apparently normal semen quality, can vary significantly in their field fertility. This study aimed to characterize the transcriptome of spermatozoa from high (HF) and...
2.
Abi Nahed R, Dhellemmes M, Payre C, Le Blevec E, Perrier J, Hennebicq S, et al.
Int J Mol Sci . 2022 Jul; 23(14). PMID: 35887380
The group X secreted phospholipase A2 (PLA2G10) is present at high levels in mouse sperm acrosome. The enzyme is secreted during capacitation and amplifies the acrosome reaction and its own...
3.
Stiavnicka M, Chaulot-Talmon A, Perrier J, Hosek P, Kenny D, Lonergan P, et al.
BMC Genomics . 2022 May; 23(1):379. PMID: 35585482
Background: Despite a multifactorial approach being taken for the evaluation of bull semen quality in many animal breeding centres worldwide, reliable prediction of bull fertility is still a challenge. Recently,...
4.
Costes V, Chaulot-Talmon A, Sellem E, Perrier J, Aubert-Frambourg A, Jouneau L, et al.
Clin Epigenetics . 2022 Apr; 14(1):54. PMID: 35477426
Background: Conflicting results regarding alterations to sperm DNA methylation in cases of spermatogenesis defects, male infertility and poor developmental outcomes have been reported in humans. Bulls used for artificial insemination...
5.
Perrier J, Kenny D, Chaulot-Talmon A, Byrne C, Sellem E, Jouneau L, et al.
Front Genet . 2020 Oct; 11:945. PMID: 33005172
In humans and model species, alterations of sperm DNA methylation patterns have been reported in cases of spermatogenesis defects, male infertility and exposure to toxins or nutritional challenges, suggesting that...
6.
Sellem E, Marthey S, Rau A, Jouneau L, Bonnet A, Perrier J, et al.
Epigenetics Chromatin . 2020 Apr; 13(1):19. PMID: 32228651
Background: Mature sperm carry thousands of RNAs, including mRNAs, lncRNAs, tRNAs, rRNAs and sncRNAs, though their functional significance is still a matter of debate. Growing evidence suggests that sperm RNAs,...
7.
Perrier J, Sellem E, Prezelin A, Gasselin M, Jouneau L, Piumi F, et al.
BMC Genomics . 2018 May; 19(1):404. PMID: 29843609
Background: Spermatozoa have a remarkable epigenome in line with their degree of specialization, their unique nature and different requirements for successful fertilization. Accordingly, perturbations in the establishment of DNA methylation...