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Jean-Philippe Kleman

Explore the profile of Jean-Philippe Kleman including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 602
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Recent Articles
1.
Vauclare P, Wulffele J, Lacroix F, Servant P, Confalonieri F, Kleman J, et al.
Nucleic Acids Res . 2024 May; 52(11):6406-6423. PMID: 38742631
Bacteria have developed a wide range of strategies to respond to stress, one of which is the rapid large-scale reorganization of their nucleoid. Nucleoid associated proteins (NAPs) are believed to...
2.
Nieto-Fabregat F, Marseglia A, Thepaut M, Kleman J, Abbas M, Le Roy A, et al.
iScience . 2024 Feb; 27(2):108792. PMID: 38299112
Due to their ability to recognize carbohydrate structures, lectins emerged as potential receptors for bacterial lipopolysaccharides (LPS). Despite growing interest in investigating the association between host receptor lectins and exogenous...
3.
Wang H, Gallet B, Moriscot C, Pezet M, Chatellard C, Kleman J, et al.
Viruses . 2023 Dec; 15(12). PMID: 38140530
HIV-1 budding as well as many other cellular processes require the Endosomal Sorting Complex Required for Transport (ESCRT) machinery. Understanding the architecture of the native ESCRT-III complex at HIV-1 budding...
4.
Wang H, Gallet B, Moriscot C, Pezet M, Chatellard C, Kleman J, et al.
bioRxiv . 2023 Oct; PMID: 37905063
HIV-1 budding as well as many other cellular processes require the Endosomal Sorting Complex Required for Transport (ESCRT) machinery. Understanding the architecture of the native ESCRT-III complex at HIV-1 budding...
5.
Abbas M, Maalej M, Nieto-Fabregat F, Thepaut M, Kleman J, Ayala I, et al.
PNAS Nexus . 2023 Oct; 2(9):pgad310. PMID: 37780233
Lipopolysaccharides are a hallmark of gram-negative bacteria, and their presence at the cell surface is key for bacterial integrity. As surface-exposed components, they are recognized by immunity C-type lectin receptors...
6.
Orsi G, Tortora M, Horard B, Baas D, Kleman J, Bucevicius J, et al.
Nat Commun . 2023 Jul; 14(1):4187. PMID: 37443316
Spermiogenesis is a radical process of differentiation whereby sperm cells acquire a compact and specialized morphology to cope with the constraints of sexual reproduction while preserving their main cargo, an...
7.
Dufour S, Tacnet-Delorme P, Kleman J, Glushonkov O, Thielens N, Bourgeois D, et al.
Commun Biol . 2023 Feb; 6(1):207. PMID: 36813842
CD47 recognized by its macrophage receptor SIRPα serves as a "don't eat-me" signal protecting viable cells from phagocytosis. How this is abrogated by apoptosis-induced changes in the plasma membrane, concomitantly...
8.
Azad K, Guilligay D, Boscheron C, Maity S, De Franceschi N, Sulbaran G, et al.
Nat Struct Mol Biol . 2023 Jan; 30(1):81-90. PMID: 36604498
The endosomal sorting complex required for transport (ESCRT) is a highly conserved protein machinery that drives a divers set of physiological and pathological membrane remodeling processes. However, the structural basis...
9.
Besson S, Laurin D, Chauviere C, Thepaut M, Kleman J, Pezet M, et al.
Biomedicines . 2022 Nov; 10(11). PMID: 36359404
Virus-like particles constitute versatile vectors that can be used as vaccine platforms in many fields from infectiology and more recently to oncology. We previously designed non-infectious adenovirus-inspired 60-mer dodecahedric virus-like...
10.
Felix J, Bumba L, Liesche C, Fraudeau A, Rebeille F, El Khoury J, et al.
Nat Commun . 2022 Sep; 13(1):5502. PMID: 36127320
Enteric bacteria have to adapt to environmental stresses in the human gastrointestinal tract such as acid and nutrient stress, oxygen limitation and exposure to antibiotics. Membrane lipid composition has recently...