Jean-Marie Ledeine
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Explore the profile of Jean-Marie Ledeine including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
2691
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0
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Recent Articles
1.
Lenz H, Van Cutsem E, Limon M, Wong K, Hendlisz A, Aglietta M, et al.
J Clin Oncol
. 2021 Oct;
40(2):161-170.
PMID: 34637336
Purpose: Nivolumab received US Food and Drug Administration approval as a single agent or in combination with ipilimumab in patients with microsatellite instability-high/mismatch repair-deficient (MSI-H/dMMR) metastatic colorectal cancer (mCRC) that...
2.
Overman M, Lonardi S, Wong K, Lenz H, Gelsomino F, Aglietta M, et al.
J Clin Oncol
. 2018 Jan;
36(8):773-779.
PMID: 29355075
Purpose Nivolumab provides clinical benefit (objective response rate [ORR], 31%; 95% CI, 20.8 to 42.9; disease control rate, 69%; 12-month overall survival [OS], 73%) in previously treated patients with DNA...
3.
Overman M, McDermott R, Leach J, Lonardi S, Lenz H, Morse M, et al.
Lancet Oncol
. 2017 Jul;
18(9):1182-1191.
PMID: 28734759
Background: Metastatic DNA mismatch repair-deficient (dMMR)/microsatellite instability-high (MSI-H) colorectal cancer has a poor prognosis after treatment with conventional chemotherapy and exhibits high levels of tumour neoantigens, tumour-infiltrating lymphocytes, and checkpoint...
4.
Harbison C, Horak C, Ledeine J, Mukhopadhyay P, Malone D, OCallaghan C, et al.
Arch Pathol Lab Med
. 2012 Oct;
137(6):820-7.
PMID: 23030695
Context: The therascreen KRAS RGQ polymerase chain reaction kit is being developed as a companion diagnostic to aid clinicians, through detection of KRAS mutations, in the identification of patients with...
5.
Rubin C, Ledeine J, Fiedorek F
Diab Vasc Dis Res
. 2008 Sep;
5(3):168-76.
PMID: 18777489
The efficacy and safety of muraglitazar versus glimepiride were evaluated in patients with type 2 diabetes. After open-label metformin monotherapy, 1,805 patients received randomised therapy with muraglitazar 2.5 mg or...
6.
Kendall D, Rubin C, Mohideen P, Ledeine J, Belder R, Gross J, et al.
Diabetes Care
. 2006 Apr;
29(5):1016-23.
PMID: 16644631
Objective: We sought to evaluate the effects of muraglitazar, a dual (alpha/gamma) peroxisome proliferator-activated receptor (PPAR) activator within the new glitazar class, on hyperglycemia and lipid abnormalities. Research Design And...
7.
Gray G, Violari A, McIntyre J, Jivkov B, Schnittman S, Reynolds L, et al.
J Acquir Immune Defic Syndr
. 2006 Apr;
42(2):169-76.
PMID: 16639342
Background: This is the first report on the preliminary efficacy of 4 different short-course nucleoside analogue regimens (stavudine [d4T], didanosine [ddI], d4T+ddI, and zidovudine [ZDV]) for the prevention of mother-to-child...
8.
Leibovitz E, Piglansky L, Raiz S, Greenberg D, Hamed K, Ledeine J, et al.
Pediatr Infect Dis J
. 2003 Nov;
22(11):943-9.
PMID: 14614364
Background: Gatifloxacin is an 8-methoxyfluoroquinolone with good activity against respiratory pathogens. Objectives: To document the bacteriologic and clinical efficacy of gatifloxacin in recurrent/nonresponsive acute otitis media (AOM). Methods: One hundred...