» Authors » Jean-Francois Desaphy

Jean-Francois Desaphy

Explore the profile of Jean-Francois Desaphy including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 97
Citations 1408
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Khalil M, Perniola V, Lanza E, Mahdi L, Sallustio P, Idone V, et al.
Int J Mol Sci . 2025 Jan; 26(2). PMID: 39859505
The integrity of esophageal epithelial cells in patients with gastroesophageal reflux disease (GERD) or GERD-like symptoms is the first mechanism of protection to decrease the sensitivity to gastric reflux and...
2.
Vicart S, Wahbi K, Duchateau J, Sellal J, Desaphy J, Deharo J, et al.
Neuromuscul Disord . 2024 Oct; 44:104464. PMID: 39368428
Mexiletine (NaMuscla™) is indicated for the symptomatic treatment of myotonia in adults with non-dystrophic myotonia. A cardiac assessment is required as mexiletine may have a pro-arrhythmic effect. Long-term safety data...
3.
Saltarella I, Altamura C, Solimando A, DAmore S, Ria R, Vacca A, et al.
Cancers (Basel) . 2024 Sep; 16(18). PMID: 39335161
Immunoglobulin (Ig) replacement therapy (IgRT) consists of the administration of low-dose human polyclonal Igs for the treatment of primary and secondary hypogammaglobulinemia that are associated with recurrent infections and immune...
4.
Canfora I, Altamura C, Desaphy J, Boccanegra B, Vailati S, Caccia C, et al.
Neurotherapeutics . 2024 Sep; 21(6):e00455. PMID: 39322473
Mexiletine is the first choice drug in the treatment of non-dystrophic myotonias. However, 30% of patients experience little benefit from mexiletine due to poor tolerability, contraindications and limited efficacy likely...
5.
Forleo C, Carella M, Basile P, Carulli E, Dadamo M, Amati F, et al.
Biomedicines . 2024 Jun; 12(6). PMID: 38927500
Arrhythmic risk stratification in patients with Lamin A/C gene (LMNA)-related cardiomyopathy influences clinical decisions. An implantable cardioverter defibrillator (ICD) should be considered in patients with an estimated 5-year risk of...
6.
Saltarella I, Link A, Lamanuzzi A, Reichen C, Robinson J, Altamura C, et al.
Biomed Pharmacother . 2024 Jun; 176:116877. PMID: 38850654
Multiple myeloma (MM) progression is closely dependent on cells in the bone marrow (BM) microenvironment, including fibroblasts (FBs) and immune cells. In their BM niche, MM cells adhere to FBs...
7.
Willis C, Calvaruso M, Angeloni D, Baatout S, Benchoua A, Bereiter-Hahn J, et al.
NPJ Microgravity . 2024 May; 10(1):50. PMID: 38693246
Periodically, the European Space Agency (ESA) updates scientific roadmaps in consultation with the scientific community. The ESA SciSpacE Science Community White Paper (SSCWP) 9, "Biology in Space and Analogue Environments",...
8.
Wahbi K, Bassez G, Duchateau J, Salort-Campana E, Vicart S, Desaphy J, et al.
Arch Cardiovasc Dis . 2024 Apr; 117(6-7):450-456. PMID: 38677940
In France, mexiletine - a class I antiarrhythmic drug - can be prescribed for the symptomatic treatment of myotonia of the skeletal muscles in adult patients with myotonic dystrophy under...
9.
Campanale C, Laghetti P, Saltarella I, Altamura C, Canioni E, Iosa E, et al.
J Neuromuscul Dis . 2024 Mar; 11(3):725-734. PMID: 38427496
Background: The nondystrophic myotonias are rare muscle hyperexcitability disorders caused by gain-of-function mutations in the SCN4A gene or loss-of-function mutations in the CLCN1 gene. Clinically, they are characterized by myotonia,...
10.
Davis T, Tabury K, Zhu S, Angeloni D, Baatout S, Benchoua A, et al.
NPJ Microgravity . 2024 Feb; 10(1):16. PMID: 38341423
Progress in mechanobiology allowed us to better understand the important role of mechanical forces in the regulation of biological processes. Space research in the field of life sciences clearly showed...