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Jean-Claude Lacherade

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Recent Articles
1.
Picard G, Loury P, Ollivier R, Guimard T, Lacherade J, Vandamme Y, et al.
Infect Dis Now . 2024 Jun; 54(5):104934. PMID: 38825046
Objectives: In our investigation of an episode of clustered acute epiglottitis occurring in Vendée, western France, between October and December 2022, we described the reported cases and confirmed its unusual...
2.
Malherbe J, Godard P, Lacherade J, Coirier V, Argaud L, Hyvernat H, et al.
Ann Intensive Care . 2024 Mar; 14(1):44. PMID: 38548917
Background: Due to aging population and increasing part of immunocompromised patients, a raise in life-threatening organ damage related to VZV can be expected. Two retrospective studies were already conducted on...
3.
Zinzoni V, Planche L, Le Potier S, Robin L, Le Parco C, Terrat P, et al.
PLoS One . 2024 Feb; 19(2):e0297349. PMID: 38330026
Background: Endotracheal tube fixation in ventilated patients must be appropriate to ensure security during mechanical ventilation and prevent skin lesions. The incidence of endotracheal tube-caused pressure ulcers ranges from 7%...
4.
Guenegou-Arnoux A, Murris J, Bechet S, Jung C, Auchabie J, Dupeyrat J, et al.
BMJ Open . 2024 Jan; 14(1):e069430. PMID: 38286691
Introduction: Fever treatment is commonly applied in patients with sepsis but its impact on survival remains undetermined. Patients with respiratory and haemodynamic failure are at the highest risk for not...
5.
Orieux A, Prevel R, Dumery M, Lascarrou J, Zucman N, Reizine F, et al.
Crit Care . 2024 Jan; 28(1):4. PMID: 38167516
Background: Group A Streptococcus is responsible for severe and potentially lethal invasive conditions requiring intensive care unit (ICU) admission, such as streptococcal toxic shock-like syndrome (STSS). A rebound of invasive...
6.
Ehrmann S, Barbier F, Demiselle J, Quenot J, Herbrecht J, Roux D, et al.
N Engl J Med . 2023 Oct; 389(22):2052-2062. PMID: 37888914
Background: Whether preventive inhaled antibiotics may reduce the incidence of ventilator-associated pneumonia is unclear. Methods: In this investigator-initiated, multicenter, double-blind, randomized, controlled, superiority trial, we assigned critically ill adults who...
7.
Vaidie J, Peju E, Jandeaux L, Lesouhaitier M, Lacherade J, Guillon A, et al.
Crit Care . 2023 Sep; 27(1):340. PMID: 37660107
Background: Except in a few retrospective studies mainly including patients under chemotherapy, information regarding the impact of immunosuppressive therapy on the prognosis of patients admitted to the intensive care unit...
8.
Francois B, Lambden S, Garaud J, Derive M, Grouin J, Asfar P, et al.
EClinicalMedicine . 2023 Jun; 60:102013. PMID: 37350989
Background: Activation of the TREM-1 pathway is associated with outcome in life threatening COVID-19. Data suggest that modulation of this pathway with nangibotide, a TREM-1 modulator may improve survival in...
9.
Patel J, Bass D, Beishuizen A, Bocca Ruiz X, Boughanmi H, Cahn A, et al.
Eur Respir J . 2022 Oct; 61(2). PMID: 36229048
Background: Granulocyte-macrophage colony-stimulating factor (GM-CSF) and dysregulated myeloid cell responses are implicated in the pathophysiology and severity of COVID-19. Methods: In this randomised, sequential, multicentre, placebo-controlled, double-blind study, adults aged...
10.
Piton G, Le Gouge A, Boisrame-Helms J, Anguel N, Argaud L, Asfar P, et al.
Intensive Care Med . 2022 Feb; 48(4):458-466. PMID: 35190840
Purpose: Acute mesenteric ischemia (AMI) is a rare, but life-threatening condition occurring among critically ill patients. Several factors have been associated with AMI, but the causal link is debated, most...