Je Won Park
Overview
Explore the profile of Je Won Park including associated specialties, affiliations and a list of published articles.
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Articles
63
Citations
606
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Recent Articles
1.
Lee N, Kang W, Kwon Y, Oh J, Jung H, Seo M, et al.
ChemMedChem
. 2022 Oct;
18(1):e202200497.
PMID: 36259357
Aminoglycosides (AGs) are broad-spectrum antibiotics used to treat bacterial infections. Over the last two decades, studies have reported the potential of AGs in the treatment of genetic disorders caused by...
2.
Lee N, Kwon Y, Kang W, Seo M, Seol Y, Park J
Enzyme Microb Technol
. 2022 Aug;
161:110113.
PMID: 35998478
Isoflavonoids are of great interest due to their human health-promoting properties, which have resulted in studies on exploiting these phytochemicals as hotspots in diverse bio -industries. Biocatalytic glycosylation of isoflavonoid...
3.
Jung H, Oh J, Kwon Y, Kang W, Seo M, Seol Y, et al.
Antioxidants (Basel)
. 2022 Jul;
11(7).
PMID: 35883887
Simple phenolics (SPs) and their glycosides have recently gained much attention as functional skin-care resources for their anti-melanogenic and antioxidant activities. Enzymatic glycosylation of SP aglycone make it feasible to...
4.
Seo M, Seol Y, Park J
J Microbiol Biotechnol
. 2022 Feb;
32(5):657-662.
PMID: 35131959
Glycosyltransferase (GT)-specific degenerate PCR screening followed by in silico sequence analyses of the target clone was used to isolate a member of family1 GT-encoding genes from the established fosmid libraries...
5.
Ban Y, Song M, Jeong J, Kwun M, Kim C, Ryu H, et al.
Front Microbiol
. 2021 Sep;
12:725916.
PMID: 34512603
With the constant emergence of multidrug-resistant gram-negative bacteria, interest in the development of new aminoglycoside (AG) antibiotics for clinical use has increased. The regioselective modification of AG scaffolds could be...
6.
Ban Y, Song M, Kim H, Lee H, Wi J, Park J, et al.
Biomolecules
. 2020 Jun;
10(6).
PMID: 32545254
The development of new aminoglycoside (AG) antibiotics has been required to overcome the resistance mechanism of AG-modifying enzymes (AMEs) of AG-resistant pathogens. The AG acetyltransferase, AAC(6')-APH(2″), one of the most...
7.
Ban Y, Song M, Hwang J, Shin H, Kim H, Hong S, et al.
Nat Chem Biol
. 2020 Jun;
16(7):810.
PMID: 32488179
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
8.
Minor components of aminoglycosides: recent advances in their biosynthesis and therapeutic potential
Ban Y, Song M, Park J, Yoon Y
Nat Prod Rep
. 2019 Sep;
37(3):301-311.
PMID: 31501843
Covering: up to 2019 There is significant demand for new aminoglycoside antibiotics due to the widespread emergence of multidrug-resistant Gram-negative bacteria and their high toxicity, but these are not easily...
9.
Ban Y, Song M, Hwang J, Shin H, Kim H, Hong S, et al.
Nat Chem Biol
. 2019 Feb;
15(5):549.
PMID: 30728495
In the version of this article originally published, reference to another structure of GenB1 was omitted (Dow, G. T., Thoden, J. B., & Holden, H. M. The three-dimensional structure of...
10.
Huong N, Lee N, Hwang H, Son H, Kim H, Seo E, et al.
J Microbiol Biotechnol
. 2019 Jan;
29(3):367-372.
PMID: 30661323
Deactivation of aminoglycosides by their modifying enzymes, including a number of aminoglycoside -phosphotransferases, is the most ubiquitous resistance mechanism in aminoglycoside-resistant pathogens. Nonetheless, in a couple of biosynthetic pathways for...