Jay Wendling
Overview
Explore the profile of Jay Wendling including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
3
Citations
263
Followers
0
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Recent Articles
1.
Liston T, Hinz S, Muller C, Holstein D, Wendling J, Melton R, et al.
Purinergic Signal
. 2020 Oct;
16(4):543-559.
PMID: 33129204
Rapid phosphoester hydrolysis of endogenous purine and pyrimidine nucleotides has challenged the characterization of the role of P2 receptors in physiology and pathology. Nucleotide phosphoester stabilization has been pursued on...
2.
Schnute M, McReynolds M, Kasten T, Yates M, Jerome G, Rains J, et al.
Biochem J
. 2012 Mar;
444(1):79-88.
PMID: 22397330
SphK (sphingosine kinase) is the major source of the bioactive lipid and GPCR (G-protein-coupled receptor) agonist S1P (sphingosine 1-phosphate). S1P promotes cell growth, survival and migration, and is a key...
3.
Gierse J, Thorarensen A, Beltey K, Bradshaw-Pierce E, Cortes-Burgos L, Hall T, et al.
J Pharmacol Exp Ther
. 2010 Apr;
334(1):310-7.
PMID: 20392816
Autotaxin is the enzyme responsible for the production of lysophosphatidic acid (LPA) from lysophosphatidyl choline (LPC), and it is up-regulated in many inflammatory conditions, including but not limited to cancer,...