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Jay R Hydren

Explore the profile of Jay R Hydren including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 229
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Recent Articles
1.
Landgren O, Prior T, Masterson T, Heuck C, Bueno O, Dash A, et al.
Blood . 2024 May; 144(4):359-367. PMID: 38768337
Estimating progression-free survival (PFS) and overall survival superiority during clinical trials of multiple myeloma (MM) has become increasingly challenging as novel therapeutics have improved patient outcomes. Thus, it is imperative...
2.
Hydren J, Lin D, Sweeney N, Wu B, Kim N, Patel S, et al.
Front Health Serv . 2024 May; 4:1354760. PMID: 38721434
Background: Advances in multiple myeloma (MM) treatment have shifted the therapeutic landscape. Understanding patients' perspectives can assist physicians in helping patients make informed decisions. This study aimed to understand the...
3.
Groot H, Broxterman R, Gifford J, Garten R, Rossman M, Jarrett C, et al.
Exp Physiol . 2022 Mar; 107(5):541-552. PMID: 35294784
New Findings: What is the central question of this study? Use of the passive leg movement (PLM) test, a non-invasive assessment of microvascular function, is on the rise. However, PLM...
4.
Chaudhari S, Sharma K, Marchetto J, Hydren J, Burton B, Moreno A
Bone Rep . 2021 Oct; 15:101141. PMID: 34692946
Background: Bone remodeling is a lifelong process that ranges from orthodontic tooth movement/alignment to bone damage/healing, to overall bone health. Osteoprotegerin (OPG) and transforming growth factor β1 (TGF-β1) are secreted...
5.
Hydren J, Gifford J, Jarrett C, Park S, Shields K, Broxterman R, et al.
Am J Physiol Regul Integr Comp Physiol . 2021 Jan; 320(4):R425-R437. PMID: 33438517
Vascular function is further attenuated in patients with chronic heart failure implanted with a continuous-flow left ventricular assist device (LVAD), likely due to decreased arterial pulsatility, and this may contribute...
6.
Trinity J, Kwon O, Broxterman R, Gifford J, Kithas A, Hydren J, et al.
Am J Physiol Heart Circ Physiol . 2020 Dec; 320(2):H668-H678. PMID: 33306447
Passive leg movement (PLM) evokes a robust and predominantly nitric oxide (NO)-mediated increase in blood flow that declines with age and disease. Consequently, PLM is becoming increasingly accepted as a...
7.
Kithas A, Broxterman R, Trinity J, Gifford J, Kwon O, Hydren J, et al.
Nitric Oxide . 2020 Sep; 104-105:51-60. PMID: 32979497
Nitric oxide synthase (NOS) inhibition with N(G)-monomethyl-l-arginine (L-NMMA) is often used to assess the role of NO in human cardiovascular function. However, the window of effect for L-NMMA on human...
8.
Jarrett C, Shields K, Broxterman R, Hydren J, Park S, Gifford J, et al.
Am J Physiol Regul Integr Comp Physiol . 2020 May; 319(1):R33-R42. PMID: 32401627
Cerebral blood flow (CBF) is commonly inferred from blood velocity measurements in the middle cerebral artery (MCA), using nonimaging, transcranial Doppler ultrasound (TCD). However, both blood velocity and vessel diameter...
9.
Hydren J, Cornwell 3rd W, Richardson R, Drakos S
ASAIO J . 2020 Mar; 66(4):339-342. PMID: 32221141
No abstract available.
10.
Park S, Kwon O, Park S, Weavil J, Hydren J, Reese V, et al.
Am J Physiol Regul Integr Comp Physiol . 2020 Feb; 318(4):R701-R711. PMID: 32022597
Recognizing the age-related decline in skeletal muscle feed artery (SMFA) vasodilatory function, this study examined the link between vasodilatory and mitochondrial respiratory function in the human vasculature. Twenty-four SMFAs were...