Jay Demas
Overview
Explore the profile of Jay Demas including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
430
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Recent Articles
1.
Tien N, Pearson J, Heller C, Demas J, Kerschensteiner D
J Neurosci
. 2015 Jul;
35(30):10815-20.
PMID: 26224863
Significance Statement: This study genetically identifies and morphologically characterizes suppressed-by-contrast retinal ganglion cells (SbC-RGCs) in mice. Targeted patch-clamp recordings from SbC-RGCs under two-photon guidance elucidate the synaptic mechanisms mediating spike...
2.
Kerschensteiner D, Liu H, Cheng C, Demas J, Cheng S, Hui C, et al.
J Neurosci
. 2008 Mar;
28(10):2342-52.
PMID: 18322081
Transcriptional programs guide the specification of neural cell types in the developing nervous system. However, it is unclear whether such programs also control specific aspects of neural circuit function at...
3.
Demas J, Cline H
Neuron
. 2007 Jan;
53(1):4-6.
PMID: 17196524
Vesicular transporters mediate the packaging of neurotransmitters into synaptic vesicles and can therefore control the amount of neurotransmitter released into the synaptic cleft. In this issue of Neuron, Smear et...
4.
Demas J, Sagdullaev B, Green E, Jaubert-Miazza L, McCall M, Gregg R, et al.
Neuron
. 2006 Apr;
50(2):247-59.
PMID: 16630836
Axon terminals from the two eyes initially overlap in the dorsal-lateral geniculate nucleus (dLGN) but subsequently refine to occupy nonoverlapping territories. Retinal activity is required to establish and maintain this...
5.
Tu D, Zhang D, Demas J, Slutsky E, Provencio I, Holy T, et al.
Neuron
. 2005 Dec;
48(6):987-99.
PMID: 16364902
Intrinsically photosensitive retinal ganglion cells (ipRGCs) mediate numerous nonvisual phenomena, including entrainment of the circadian clock to light-dark cycles, pupillary light responsiveness, and light-regulated hormone release. We have applied multielectrode...
6.
Stacy R, Demas J, Burgess R, Sanes J, Wong R
J Neurosci
. 2005 Oct;
25(41):9347-57.
PMID: 16221843
Many developing neural circuits generate synchronized bursting activity among neighboring neurons, a pattern thought to be important for sculpting precise neural connectivity. Network output remains relatively constant as the cellular...
7.
Eglen S, Demas J, Wong R
Neuron
. 2003 Dec;
40(6):1053-5.
PMID: 14687538
A role for spontaneous spiking activity in shaping neuronal circuits has frequently been debated. Analyses of retinotopy in mutant mice with reduced correlated firing among neighboring retinal cells by Grubb...
8.
Demas J, Eglen S, Wong R
J Neurosci
. 2003 Apr;
23(7):2851-60.
PMID: 12684472
In the immature retina, correlated spontaneous activity in the form of propagating waves is thought to be necessary for the refinement of connections between the retina and its targets. The...
9.
Kettunen P, Demas J, Lohmann C, Kasthuri N, Gong Y, Wong R, et al.
J Neurosci Methods
. 2002 Sep;
119(1):37-43.
PMID: 12234633
The use of fluorescence-based calcium indicators has, over the years, unraveled important calcium-dependent mechanisms underlying neuronal function and development. However, difficulties associated with the loading of calcium indicators have limited...