Jay A Gingrich
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Explore the profile of Jay A Gingrich including associated specialties, affiliations and a list of published articles.
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51
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3748
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Recent Articles
1.
Kildegaard H, Bliddal M, Ernst M, Sander S, Wesselhoeft R, Gingrich J, et al.
Mol Psychiatry
. 2024 Dec;
PMID: 39658704
Preclinical data suggest that gestational exposure to selective serotonin reuptake inhibitors (SSRI) alter gut innervation, and delays colonic motility. In this study we investigated associations between gestational SSRI exposure and...
2.
Bliddal M, Wesselhoeft R, Strandberg-Larsen K, Ernst M, Weissman M, Gingrich J, et al.
Child Adolesc Psychiatry Ment Health
. 2023 Jun;
17(1):73.
PMID: 37328889
Background: Selective serotonin reuptake inhibitors (SSRIs) are the most frequently prescribed antidepressants in pregnancy. Animal and some clinical studies have suggested potential increases in depression and anxiety following prenatal SSRI...
3.
Pekarskaya E, Holt E, Gingrich J, Ansorge M, Javitch J, Canetta S
Sci Rep
. 2021 Nov;
11(1):22852.
PMID: 34819526
Depression and anxiety, two of the most common mental health disorders, share common symptoms and treatments. Most pharmacological agents available to treat these disorders target monoamine systems. Currently, finding the...
4.
Tottenham N, Weissman M, Wang Z, Warner V, Gameroff M, Semanek D, et al.
Biol Psychiatry Cogn Neurosci Neuroimaging
. 2021 Jan;
6(3):343-351.
PMID: 33487578
Background: Major depressive disorder (MDD) is associated with aberrant limbic neural responses to emotional stimuli. We assessed how self-generated emotions modulate trial-by-trial limbic activity and whether this brain-emotion synchrony varies...
5.
Jaggar M, Banerjee T, Weisstaub N, Gingrich J, Vaidya V
Neuronal Signal
. 2020 Jul;
3(1):NS20180205.
PMID: 32714597
Acute treatment with the selective serotonin reuptake inhibitor (SSRI), fluoxetine (Flx), induces anxiety-like behavioral effects. The serotonin receptor (5-HT) is implicated in the modulation of anxiety-like behavior, however its contribution...
6.
Fanibunda S, Deb S, Maniyadath B, Tiwari P, Ghai U, Gupta S, et al.
Proc Natl Acad Sci U S A
. 2019 May;
116(22):11028-11037.
PMID: 31072928
Mitochondria in neurons, in addition to their primary role in bioenergetics, also contribute to specialized functions, including regulation of synaptic transmission, Ca homeostasis, neuronal excitability, and stress adaptation. However, the...
7.
Demireva E, Suri D, Morelli E, Mahadevia D, Chuhma N, Teixeira C, et al.
Mol Psychiatry
. 2018 Aug;
25(12):3304-3321.
PMID: 30120415
Serotonin (5-HT) selective reuptake inhibitors (SSRIs) are widely used in the treatment of depression and anxiety disorders, but responsiveness is uncertain and side effects often lead to discontinuation. Side effect...
8.
Lugo-Candelas C, Cha J, Hong S, Bastidas V, Weissman M, Fifer W, et al.
JAMA Pediatr
. 2018 Apr;
172(6):525-533.
PMID: 29630692
Importance: Selective serotonin reuptake inhibitor (SSRI) use among pregnant women is increasing, yet the association between prenatal SSRI exposure and fetal neurodevelopment is poorly understood. Animal studies show that perinatal...
9.
Gingrich J, Malm H, Ansorge M, Brown A, Sourander A, Suri D, et al.
Birth Defects Res
. 2017 Jul;
109(12):924-932.
PMID: 28714607
Development passes through sensitive periods, during which plasticity allows for genetic and environmental factors to exert indelible influence on the maturation of the organism. In the context of central nervous...
10.
Jaggar M, Weisstaub N, Gingrich J, Vaidya V
Neurobiol Stress
. 2017 Jun;
7:89-102.
PMID: 28626787
Chronic stress enhances risk for psychiatric disorders, and in animal models is known to evoke depression-like behavior accompanied by perturbed neurohormonal, metabolic, neuroarchitectural and transcriptional changes. Serotonergic neurotransmission, including serotonin...