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Javier Vina-Gonzalez

Explore the profile of Javier Vina-Gonzalez including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 52
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Recent Articles
1.
Dolz M, Monterrey D, Quartinello F, de Santos P, Mateljak I, Pellis A, et al.
ACS Omega . 2024 Nov; 9(45):45633-45640. PMID: 39554451
Plastic waste is a major threat in our industrialized world and is driving research into bioplastics. The success of biobased polyethylene furanoate (PEF) as a viable alternative to polyethylene terephthalate...
2.
Dolz M, Monterrey D, Beltran-Nogal A, Menes-Rubio A, Keser M, Gonzalez-Perez D, et al.
Methods Enzymol . 2023 Nov; 693:73-109. PMID: 37977739
Fungal unspecific peroxygenases (UPOs) are arising as versatile biocatalysts for C-H oxyfunctionalization reactions. In recent years, several directed evolution studies have been conducted to design improved UPO variants. An essential...
3.
Vina-Gonzalez J, Alcalde M
Methods Enzymol . 2020 Sep; 643:1-13. PMID: 32896276
Employing the homologous DNA recombination apparatus of Saccharomyces cerevisiae as a dynamic engineering tool allows mutant libraries to be constructed in a rapid and efficient manner. Among the plethora of...
4.
Vina-Gonzalez J, Alcalde M
Comput Struct Biotechnol J . 2020 Jul; 18:1800-1810. PMID: 32695272
Aryl-alcohol oxidase (AAO) is a fungal GMC flavoprotein secreted by white-rot fungi that supplies HO to the ligninolytic consortium. This enzyme can oxidize a wide array of aromatic alcohols in...
5.
Vina-Gonzalez J, Martinez A, Guallar V, Alcalde M
Biochim Biophys Acta Proteins Proteom . 2019 Nov; 1868(1):140293. PMID: 31676448
Furan-2,5-dicarboxylic acid (FDCA) is a building block of biodegradable plastics that can be used to replace those derived from fossil carbon sources. In recent years, much interest has focused on...
6.
Vina-Gonzalez J, Elbl K, Ponte X, Valero F, Alcalde M
Biotechnol Bioeng . 2018 Mar; 115(7):1666-1674. PMID: 29532900
Aryl-alcohol oxidase (AAO) plays a fundamental role in the fungal ligninolytic secretome, acting as a supplier of H O . Despite its highly selective mechanism of action, the presence of...
7.
Vina-Gonzalez J, Gonzalez-Perez D, Alcalde M
J Vis Exp . 2016 Apr; (110):e53761. PMID: 27077451
Directed evolution in Saccharomyces cerevisiae offers many attractive advantages when designing enzymes for biotechnological applications, a process that involves the construction, cloning and expression of mutant libraries, coupled to high...
8.
Molina-Espeja P, Vina-Gonzalez J, Gomez-Fernandez B, Martin-Diaz J, Garcia-Ruiz E, Alcalde M
Biotechnol Adv . 2016 Apr; 34(5):754-767. PMID: 27064127
For more than thirty years, biotechnology has borne witness to the power of directed evolution in designing molecules of industrial relevance. While scientists all over the world discuss the future...
9.
Vina-Gonzalez J, Gonzalez-Perez D, Ferreira P, Martinez A, Alcalde M
Appl Environ Microbiol . 2015 Jul; 81(18):6451-62. PMID: 26162870
Aryl-alcohol oxidase (AAO) is an extracellular flavoprotein that supplies ligninolytic peroxidases with H2O2 during natural wood decay. With a broad substrate specificity and highly stereoselective reaction mechanism, AAO is an...