Javier Olascoaga
Overview
Explore the profile of Javier Olascoaga including associated specialties, affiliations and a list of published articles.
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52
Citations
1200
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Recent Articles
1.
Vitkova M, Diouf I, Malpas C, Horakova D, Kubala Havrdova E, Patti F, et al.
Neurology
. 2022 Apr;
98(24):e2401-e2412.
PMID: 35410900
Background And Objectives: The severity of multiple sclerosis (MS) varies widely among individuals. Understanding the determinants of this heterogeneity will help clinicians optimize the management of MS. The aim of...
2.
Kalincik T, Diouf I, Sharmin S, Malpas C, Spelman T, Horakova D, et al.
Neurology
. 2020 Dec;
96(5):e783-e797.
PMID: 33372028
Objective: To test the hypothesis that immunotherapy prevents long-term disability in relapsing-remitting multiple sclerosis (MS), we modeled disability outcomes in 14,717 patients. Methods: We studied patients from MSBase followed for...
3.
Roos I, Leray E, Frascoli F, Casey R, Brown J, Horakova D, et al.
Brain
. 2020 Sep;
143(9):2742-2756.
PMID: 32947619
In multiple sclerosis, treatment start or switch is prompted by evidence of disease activity. Whilst immunomodulatory therapies reduce disease activity, the time required to attain maximal effect is unclear. In...
4.
Malpas C, Manouchehrinia A, Sharmin S, Roos I, Horakova D, Kubala Havrdova E, et al.
Brain
. 2020 May;
143(5):1400-1413.
PMID: 32386427
Patients with the 'aggressive' form of multiple sclerosis accrue disability at an accelerated rate, typically reaching Expanded Disability Status Score (EDSS) ≥ 6 within 10 years of symptom onset. Several...
5.
Kunchok A, Malpas C, Nytrova P, Kubala Havrdova E, Alroughani R, Terzi M, et al.
Mult Scler Relat Disord
. 2019 Dec;
38:101868.
PMID: 31877445
Background: Aquaporin-4-IgG positive (AQP4-IgG+) Neuromyelitis Optica Spectrum Disorder (NMOSD) is an uncommon central nervous system autoimmune disorder. Disease outcomes in AQP4-IgG+NMOSD are typically measured by relapse rate and disability. Using...
6.
Lopetegi I, Munoz-Lopetegi A, Arruti M, Prada A, Urcelay S, Olascoaga J, et al.
Mult Scler J Exp Transl Clin
. 2019 Dec;
5(4):2055217319888957.
PMID: 31798940
Background: The relation between ABO/Rh groups and multiple sclerosis (MS) has been proposed in several studies, however there is a controversy about the role of these groups in the disease....
7.
Zhou Y, Claflin S, Stankovich J, van der Mei I, Simpson Jr S, Roxburgh R, et al.
Mult Scler
. 2019 Nov;
26(13):1765-1774.
PMID: 31668127
Background: The Multiple Sclerosis Severity Score (MSSS) is a widely used measure of the disability progression rate. However, the global MSSS may not be the best basis for comparison between...
8.
Fambiatos A, Jokubaitis V, Horakova D, Kubala Havrdova E, Trojano M, Prat A, et al.
Mult Scler
. 2019 Aug;
26(1):79-90.
PMID: 31397221
Background: The risk factors for conversion from relapsing-remitting to secondary progressive multiple sclerosis remain highly contested. Objective: The aim of this study was to determine the demographic, clinical and paraclinical...
9.
Nguyen A, Kubala Havrdova E, Horakova D, Izquierdo G, Kalincik T, van der Walt A, et al.
Mult Scler Relat Disord
. 2019 Jan;
28:235-243.
PMID: 30623864
Background: Exposure to disease-modifying therapy (DMT) during early pregnancy in women with relapsing-remitting MS (RRMS) may be increasing. Objective: To retrospectively determine incidence of pregnancy, DMT exposure and pregnancy outcomes...
10.
Saenz-Cuesta M, Alberro A, Munoz-Culla M, Osorio-Querejeta I, Fernandez-Mercado M, Lopetegui I, et al.
Int J Mol Sci
. 2018 Aug;
19(8).
PMID: 30126230
Extracellular vesicles (EVs) are membrane-bound particles involved in intercellular communication. They carry proteins, lipids, and nucleotides such as microRNAs (miRNAs) from the secreting cell that can modulate target cells. We...