Jason W Bauer
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Explore the profile of Jason W Bauer including associated specialties, affiliations and a list of published articles.
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9
Citations
1174
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Recent Articles
1.
Palanichamy A, Bauer J, Yalavarthi S, Meednu N, Barnard J, Owen T, et al.
J Immunol
. 2014 Jan;
192(3):906-18.
PMID: 24379124
Inappropriate activation of type I IFN plays a key role in the pathogenesis of autoimmune disease, including systemic lupus erythematosus (SLE). In this study, we report the presence of IFN...
2.
Bilgic H, Ytterberg S, Amin S, McNallan K, Wilson J, Koeuth T, et al.
Arthritis Rheum
. 2009 Oct;
60(11):3436-46.
PMID: 19877033
Objective: Up-regulation of whole blood type I interferon (IFN)-driven transcripts and chemokines has been described in a number of autoimmune diseases. An IFN gene expression "signature" is a candidate biomarker...
3.
Bauer J, Petri M, Batliwalla F, Koeuth T, Wilson J, Slattery C, et al.
Arthritis Rheum
. 2009 Oct;
60(10):3098-107.
PMID: 19790071
Objective: Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by unpredictable flares of disease activity and irreversible damage to multiple organ systems. An earlier study showed that SLE...
4.
Bauer J, Bilgic H, Baechler E
Nat Rev Rheumatol
. 2009 May;
5(5):257-65.
PMID: 19412192
Gene-expression profiling is a powerful tool for the discovery of molecular fingerprints that underlie human disease. Microarray technologies allow the analysis of messenger RNA transcript levels for every gene in...
5.
Busconi L, Bauer J, Tumang J, Laws A, Perkins-Mesires K, Tabor A, et al.
J Immunol
. 2007 Nov;
179(11):7397-405.
PMID: 18025183
We have previously shown that rheumatoid factors produced by Fas-deficient autoimmune-prone mice typically bind autologous IgG2a with remarkably low affinity. Nevertheless, B cells representative of this rheumatoid factor population proliferate...
6.
Baechler E, Bauer J, Slattery C, Ortmann W, Espe K, Novitzke J, et al.
Mol Med
. 2007 May;
13(1-2):59-68.
PMID: 17515957
Recent studies have shown increased expression of interferon (IFN)-regulated genes in the peripheral blood cells of patients with systemic lupus erythematosus. A similar interferon signature has been observed in affected...
7.
Graham R, Kyogoku C, Sigurdsson S, Vlasova I, Davies L, Baechler E, et al.
Proc Natl Acad Sci U S A
. 2007 Apr;
104(16):6758-63.
PMID: 17412832
Systematic genome-wide studies to map genomic regions associated with human diseases are becoming more practical. Increasingly, efforts will be focused on the identification of the specific functional variants responsible for...
8.
Bauer J, Baechler E, Petri M, Batliwalla F, Crawford D, Ortmann W, et al.
PLoS Med
. 2006 Dec;
3(12):e491.
PMID: 17177599
Background: Systemic lupus erythematosus (SLE) is a serious systemic autoimmune disorder that affects multiple organ systems and is characterized by unpredictable flares of disease. Recent evidence indicates a role for...
9.
Graham R, Kozyrev S, Baechler E, Reddy M, Plenge R, Bauer J, et al.
Nat Genet
. 2006 Apr;
38(5):550-5.
PMID: 16642019
Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by activation of the type I interferon (IFN) pathway. Here we convincingly replicate association of the IFN regulatory factor 5...