Jason T George
Overview
Explore the profile of Jason T George including associated specialties, affiliations and a list of published articles.
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Articles
34
Citations
668
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Recent Articles
11.
Mattei F, George J, Jolly M
Front Immunol
. 2023 Aug;
14:1253551.
PMID: 37533861
No abstract available.
12.
Najafi A, Jolly M, George J
iScience
. 2023 Jul;
26(7):106964.
PMID: 37426354
The Epithelial-to-Mesenchymal Transition (EMT) is a hallmark of cancer metastasis and morbidity. EMT is a non-binary process, and cells can be stably arrested en route to EMT in an intermediate...
13.
George J, Levine H
Elife
. 2023 Apr;
12.
PMID: 37096883
The failure of cancer treatments, including immunotherapy, continues to be a major obstacle in preventing durable remission. This failure often results from tumor evolution, both genotypic and phenotypic, away from...
14.
Jain P, Corbo S, Mohammad K, Sahoo S, Ranganathan S, George J, et al.
J R Soc Interface
. 2023 Jan;
20(198):20220627.
PMID: 36628532
Epithelial-mesenchymal transition (EMT) and its reverse mesenchymal-epithelial transition (MET) are critical during embryonic development, wound healing and cancer metastasis. While phenotypic changes during short-term EMT induction are reversible, long-term EMT...
15.
Lin X, George J, Schafer N, Chau K, Birnbaum M, Clementi C, et al.
Nat Comput Sci
. 2022 Sep;
1(5):362-373.
PMID: 36090450
Accurate assessment of TCR-antigen specificity at the whole immune repertoire level lies at the heart of improved cancer immunotherapy, but predictive models capable of high-throughput assessment of TCR-peptide pairs are...
16.
Chau K, George J, Onuchic J, Lin X, Levine H
Phys Rev E
. 2022 Aug;
106(1-1):014406.
PMID: 35974642
The T-cell arm of the adaptive immune system provides the host protection against unknown pathogens by discriminating between host and foreign material. This discriminatory capability is achieved by the creation...
17.
Masuda H, Harano K, Miura S, Wang Y, Hirota Y, Harada O, et al.
JCO Precis Oncol
. 2022 Mar;
6:e2000368.
PMID: 35294223
Purpose: Lehmann et al have identified four molecular subtypes of triple-negative breast cancer (TNBC)-basal-like (BL) 1, BL2, mesenchymal (M), and luminal androgen receptor-and an immunomodulatory (IM) gene expression signature modifier....
18.
Mandal S, Tejaswi T, Janivara R, Srikrishnan S, Thakur P, Sahoo S, et al.
Biomolecules
. 2022 Jan;
12(1).
PMID: 35053177
Epithelial-mesenchymal plasticity (EMP) underlies embryonic development, wound healing, and cancer metastasis and fibrosis. Cancer cells exhibiting EMP often have more aggressive behavior, characterized by drug resistance, and tumor-initiating and immuno-evasive...
19.
Chakraborty P, George J, Woodward W, Levine H, Jolly M
Transl Oncol
. 2021 Feb;
14(4):101026.
PMID: 33535154
Inflammatory breast cancer (IBC) is a highly aggressive breast cancer that metastasizes largely via tumor emboli, and has a 5-year survival rate of less than 30%. No unique genomic signature...
20.
George J, Levine H
Trends Cancer
. 2021 Jan;
7(4):373-383.
PMID: 33446448
Cancer represents a diverse collection of diseases characterized by heterogeneous cell populations that dynamically evolve in their environment. As painfully evident in cases of treatment failure and recurrence, this general...