Jason N Busby
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Explore the profile of Jason N Busby including associated specialties, affiliations and a list of published articles.
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8
Citations
200
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Recent Articles
1.
Busby J, Trevelyan S, Pegg C, Kerr E, Schulz B, Chassagnon I, et al.
IUCrJ
. 2024 Mar;
11(Pt 3):299-308.
PMID: 38512773
Bacterial ABC toxin complexes (Tcs) comprise three core proteins: TcA, TcB and TcC. The TcA protein forms a pentameric assembly that attaches to the surface of target cells and penetrates...
2.
Piper S, Brillault L, Rothnagel R, Croll T, Box J, Chassagnon I, et al.
Nat Commun
. 2019 Apr;
10(1):1952.
PMID: 31028251
ABC toxins are pore-forming virulence factors produced by pathogenic bacteria. YenTcA is the pore-forming and membrane binding A subunit of the ABC toxin YenTc, produced by the insect pathogen Yersinia...
3.
Jackson V, Busby J, Janssen B, Lott J, Seiradake E
Front Neurosci
. 2019 Apr;
13:183.
PMID: 30930731
Pioneering bioinformatic analysis using sequence data revealed that teneurins evolved from bacterial tyrosine-aspartate (YD)-repeat protein precursors. Here, we discuss how structures of the C-terminal domain of teneurins, determined using -ray...
4.
Gebhard S, Busby J, Fritz G, Moreland N, Cook G, Lott J, et al.
J Bacteriol
. 2014 Jul;
196(19):3472-81.
PMID: 25049090
Bacterial uptake of phosphate is usually accomplished via high-affinity transporters that are commonly regulated by two-component systems, which are activated when the concentration of phosphate is low. Mycobacterium smegmatis possesses...
5.
Busby J, Panjikar S, Landsberg M, Hurst M, Lott J
Nature
. 2013 Aug;
501(7468):547-50.
PMID: 23913273
The ABC toxin complexes produced by certain bacteria are of interest owing to their potent insecticidal activity and potential role in human disease. These complexes comprise at least three proteins...
6.
Landsberg M, Jones S, Rothnagel R, Busby J, Marshall S, Simpson R, et al.
Proc Natl Acad Sci U S A
. 2011 Dec;
108(51):20544-9.
PMID: 22158901
Toxin complex (Tc) proteins are a class of bacterial protein toxins that form large, multisubunit complexes. Comprising TcA, B, and C components, they are of great interest because many exhibit...
7.
Busby J, Landsberg M, Simpson R, Jones S, Hankamer B, Hurst M, et al.
J Mol Biol
. 2011 Nov;
415(2):359-71.
PMID: 22108167
Yersinia entomophaga MH96 is a native New Zealand soil bacterium that secretes a large ABC-type protein toxin complex, Yen-Tc, similar to those produced by nematode-associated bacteria such as Photorhabdus luminescens....
8.
Goodwin T, Busby J, Poulter R
BMC Genomics
. 2007 Aug;
8:263.
PMID: 17683538
Background: Target-primed (non-LTR) retrotransposons, such as the human L1 element, are mobile genetic elements found in many eukaryotic genomes. They are often present in large numbers and their retrotransposition can...