Jason M Robotham
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Explore the profile of Jason M Robotham including associated specialties, affiliations and a list of published articles.
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18
Citations
549
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Recent Articles
1.
Zhao L, Zhao L, Zhang B, Robotham J, Roux K, Tang H
PLoS One
. 2017 Aug;
12(8):e0182935.
PMID: 28800361
Allergy to peanuts has become a common and severe problem, especially in westernized countries. In this study, we evaluated the target and epitope specificity of the capture and detection mouse...
2.
Wu X, Lee E, Hammack C, Robotham J, Basu M, Lang J, et al.
J Virol
. 2014 May;
88(15):8433-44.
PMID: 24829338
Unlabelled: The molecular mechanism of the hepatic tropism of hepatitis C virus (HCV) remains incompletely defined. In vitro hepatic differentiation of pluripotent stem cells produces hepatocyte-like cells (HLCs) permissive for...
3.
Nag A, Robotham J, Tang H
J Virol
. 2012 Sep;
86(23):12616-24.
PMID: 22973029
Nonstructural protein 5A (NS5A) of hepatitis C virus (HCV) is an indispensable component of the HCV replication and assembly machineries. Although its precise mechanism of action is not yet clear,...
4.
Wu X, Robotham J, Lee E, Dalton S, Kneteman N, Gilbert D, et al.
PLoS Pathog
. 2012 Apr;
8(4):e1002617.
PMID: 22496645
Primary human hepatocytes isolated from patient biopsies represent the most physiologically relevant cell culture model for hepatitis C virus (HCV) infection, but these primary cells are not readily accessible, display...
5.
Yang F, Robotham J, Grise H, Frausto S, Madan V, Zayas M, et al.
PLoS Pathog
. 2010 Oct;
6(9):e1001118.
PMID: 20886100
Since the advent of genome-wide small interfering RNA screening, large numbers of cellular cofactors important for viral infection have been discovered at a rapid pace, but the viral targets and...
6.
Xia L, Willison L, Porter L, Robotham J, Teuber S, Sathe S, et al.
Mol Immunol
. 2010 Apr;
47(9):1808-16.
PMID: 20362338
The 11S globulins are members of the cupin protein superfamily and represent an important class of tree nut allergens for which a number of linear epitopes have been mapped. However,...
7.
Robotham J, Xia L, Willison L, Teuber S, Sathe S, Roux K
Mol Immunol
. 2010 Apr;
47(9):1830-8.
PMID: 20362336
Both linear and conformational epitopes likely contribute to the allergenicity of tree nut allergens, yet, due largely to technical issues, few conformational epitopes have been characterized. Using the well studied...
8.
Robotham J, Hoffman G, Teuber S, Beyer K, Sampson H, Sathe S, et al.
Mol Immunol
. 2009 Jul;
46(15):2975-84.
PMID: 19631385
Allergic reactions to walnuts and hazelnuts can be serious. The 11S globulins (legumins) have been identified as important allergens in these and other nuts and seeds. Here we identify the...
9.
Liu Z, Robida J, Chinnaswamy S, Yi G, Robotham J, Nelson H, et al.
Hepatology
. 2009 Jun;
50(1):25-33.
PMID: 19489073
Unlabelled: Hepatitis C virus (HCV) infection leads to acute and chronic liver diseases, and new classes of anti-HCV therapeutics are needed. Cyclosporine A (CsA) inhibits HCV replication and CsA derivatives...
10.
Liu Z, Yang F, Robotham J, Tang H
J Virol
. 2009 Apr;
83(13):6554-65.
PMID: 19386705
Replication of hepatitis C virus (HCV) RNA occurs on intracellular membranes, and the replication complex (RC) contains viral RNA, nonstructural proteins, and cellular cofactors. We previously demonstrated that cyclophilin A...