Jason M McEwen
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Explore the profile of Jason M McEwen including associated specialties, affiliations and a list of published articles.
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5
Citations
292
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Recent Articles
1.
Zhang K, Tan L, Pellegrini M, Zipursky S, McEwen J
Cell Rep
. 2016 Feb;
14(5):1258-1271.
PMID: 26832407
A common step in the formation of neural circuits is the conversion of growth cones to presynaptic terminals. Characterizing patterns of global gene expression during this process is problematic due...
2.
Tan L, Zhang K, Pecot M, Nagarkar-Jaiswal S, Lee P, Takemura S, et al.
Cell
. 2015 Dec;
163(7):1756-69.
PMID: 26687360
Information processing relies on precise patterns of synapses between neurons. The cellular recognition mechanisms regulating this specificity are poorly understood. In the medulla of the Drosophila visual system, different neurons...
3.
McEwen J, Kaplan J
Mol Biol Cell
. 2008 Jul;
19(9):3836-46.
PMID: 18596236
The SM protein UNC-18 has been proposed to regulate several aspects of secretion, including synaptic vesicle docking, priming, and fusion. Here, we show that UNC-18 has a chaperone function in...
4.
Chun D, McEwen J, Burbea M, Kaplan J
Mol Biol Cell
. 2008 Apr;
19(7):2682-95.
PMID: 18434599
After endocytosis, membrane proteins are often sorted between two alternative pathways: a recycling pathway and a degradation pathway. Relatively little is known about how trafficking through these alternative pathways is...
5.
McEwen J, Madison J, Dybbs M, Kaplan J
Neuron
. 2006 Aug;
51(3):303-15.
PMID: 16880125
Priming of synaptic vesicles (SVs) is essential for synaptic transmission. UNC-13 proteins are required for priming. Current models propose that UNC-13 stabilizes the open conformation of Syntaxin, in which the...