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Jason Lenox-Krug

Explore the profile of Jason Lenox-Krug including associated specialties, affiliations and a list of published articles. Areas
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Citations 40
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Recent Articles
1.
Criswell S, Searles Nielsen S, Faust I, Shimony J, White 3rd R, Lenox-Krug J, et al.
Neurotoxicology . 2023 May; 97:25-33. PMID: 37127223
Objective: To evaluate in-vivo neuroinflammation and white matter (WM) microstructural integrity in occupational manganese (Mn) exposure. Methods: We assessed brain inflammation using Diffusion Basis Spectrum Imaging (DBSI) in 26 Mn-exposed...
2.
Criswell S, Searles Nielsen S, Dlamini W, Warden M, Perlmutter J, Sheppard L, et al.
Toxicol Sci . 2021 Apr; 182(1):132-141. PMID: 33881537
The relationships between the neurotoxicant manganese (Mn), dopaminergic pathology, and parkinsonism remain unclear. Therefore, we used [11C](N-methyl)benperidol (NMB) positron emission tomography to investigate the associations between Mn exposure, striatal and...
3.
Criswell S, Searles Nielsen S, Warden M, Perlmutter J, Moerlein S, Sheppard L, et al.
J Occup Environ Med . 2020 May; 62(10):788-794. PMID: 32472844
Objective: To understand the neurotoxic effects of manganese (Mn) exposure on monoaminergic function, utilizing [C]dihydrotetrabenazine (DTBZ) positron emission tomography (PET) to measure vesicular monoamine transporter 2 (VMAT2). Methods: Basal ganglia...
4.
Criswell S, Searles Nielsen S, Warden M, Flores H, Lenox-Krug J, Racette S, et al.
J Occup Environ Med . 2019 Jul; 61(8):641-645. PMID: 31348423
Objective: T1-weighted brain magnetic resonance imaging (MRI) of the basal ganglia provides a noninvasive measure of manganese (Mn) exposure, and may also represent a biomarker for clinical neurotoxicity. Methods: We...
5.
Criswell S, Warden M, Searles Nielsen S, Perlmutter J, Moerlein S, Sheppard L, et al.
Neurology . 2018 Aug; 91(11):e1022-e1030. PMID: 30097475
Objective: To investigate the associations between manganese (Mn) exposure, D2 dopamine receptors (D2Rs), and parkinsonism using [C](N-methyl)benperidol (NMB) PET. Methods: We used NMB PET to evaluate 50 workers with a...