Jason I Comander
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Explore the profile of Jason I Comander including associated specialties, affiliations and a list of published articles.
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10
Citations
81
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0
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Recent Articles
1.
Michaelides M, Besirli C, Yang Y, de Guimaraes T, Wong S, Huckfeldt R, et al.
Am J Ophthalmol
. 2024 Jun;
267:122-134.
PMID: 38871269
Purpose: To assess the safety and efficacy of AAV5-hRKp.RPGR in participants with retinitis pigmentosa GTPase regulator (RPGR)-associated X-linked retinitis pigmentosa (XLRP). Design: Open-label, phase 1/2 dose escalation/expansion study (ClinicalTrials.gov Identifier:...
2.
Pierce E, Aleman T, Jayasundera K, Ashimatey B, Kim K, Rashid A, et al.
N Engl J Med
. 2024 May;
390(21):1972-1984.
PMID: 38709228
Background: -associated inherited retinal degeneration causes severe early-onset vision loss due to pathogenic variants in . EDIT-101 is a clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated protein 9 (Cas9) gene-editing...
3.
Wang J, Qian C, Comander J
Ophthalmic Surg Lasers Imaging Retina
. 2024 Jan;
55(1):9-11.
PMID: 38189797
No abstract available.
4.
Park E, Huckfeldt R, Comander J, Sobrin L
J Vitreoretin Dis
. 2023 Apr;
5(2):147-156.
PMID: 37009079
Purpose: This report illustrates that peripheral vascular leakage on ultra-widefield fluorescein angiography (FA) can occur in patients with inherited retinal degeneration (IRD) without evidence of a separate cause of leakage....
5.
Pennesi M, Yang P, Birch D, Weng C, Moore A, Iannaccone A, et al.
Ophthalmol Retina
. 2022 Jul;
6(12):1130-1144.
PMID: 35781068
Purpose: To evaluate the safety and efficacy of rAAV2tYF-CB-hRS1, a recombinant adeno-associated virus vector expressing retinoschisin (RS1), in individuals with retinal disease caused by mutations in the RS1 gene. Design:...
6.
Wang J, Qian C, Comander J
Ophthalmic Surg Lasers Imaging Retina
. 2022 Apr;
53(4):182-184.
PMID: 35417295
Rhegmatogenous retinal detachment in choroideremia is a rare occurrence. The authors present a case of a 23-year-old man with choroideremia with a near-total rhegmatogenous retinal detachment. Fundus examination did not...
7.
Catomeris A, Ballios B, Sangermano R, Wagner N, Comander J, Pierce E, et al.
Ophthalmic Genet
. 2022 Jan;
43(3):332-339.
PMID: 35057699
Background: Variants in were recently described to cause a retinal dystrophy with only eight families described to date and a predominant phenotype of macular atrophy and peripheral reticular degeneration. Here,...
8.
Ballios B, Place E, Martinez-Velazquez L, Pierce E, Comander J, Huckfeldt R
Genes (Basel)
. 2021 Dec;
12(12).
PMID: 34946802
Sector and pericentral are two rare, regional forms of retinitis pigmentosa (RP). While usually defined as stable or only very slowly progressing, the available literature to support this claim is...
9.
Huckfeldt R, Grigorian F, Place E, Comander J, Vavvas D, Young L, et al.
Mol Vis
. 2020 Jun;
26:423-433.
PMID: 32565670
Purpose: To evaluate the phenotypic spectrum of autosomal recessive associated retinal dystrophies and assess genotypic associations. Methods: A retrospective multicenter study was performed of patients with biallelic -associated retinal dystrophies....
10.
Carvalho L, Xiao R, Wassmer S, Langsdorf A, Zinn E, Pacouret S, et al.
Hum Gene Ther
. 2018 Jan;
29(7):771-784.
PMID: 29325457
Gene therapy is a promising approach in the treatment of inherited and common complex disorders of the retina. Preclinical and clinical studies have validated the use of adeno-associated viral vectors...