Jason E Aten
Overview
Explore the profile of Jason E Aten including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
349
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Recent Articles
1.
Weighted gene co-expression network analysis identifies biomarkers in glycerol kinase deficient mice
MacLennan N, Dong J, Aten J, Horvath S, Rahib L, Ornelas L, et al.
Mol Genet Metab
. 2009 Jun;
98(1-2):203-14.
PMID: 19546021
Symptomatic glycerol kinase deficiency (GKD) is associated with episodic metabolic and central nervous system deterioration. We report here the first application of weighted gene co-expression network analysis (WGCNA) to investigate...
2.
Farber C, Aten J, Farber E, de Vera V, Gularte R, Islas-Trejo A, et al.
Physiol Genomics
. 2009 Apr;
37(3):294-302.
PMID: 19336533
HG.CAST-(D9Mit249-D9Mit133) (HG9) congenic mice are homozygous for CAST/EiJ chromosome (Chr) 9 alleles from approximately 9 to 84 Mbp on a C57BL6/J-hg/hg (HG) background. This region contains the carcass fat in...
3.
Farber C, van Nas A, Ghazalpour A, Aten J, Doss S, Sos B, et al.
J Bone Miner Res
. 2008 Sep;
24(1):105-16.
PMID: 18767929
Numerous quantitative trait loci (QTLs) affecting bone traits have been identified in the mouse; however, few of the underlying genes have been discovered. To improve the process of transitioning from...
4.
Aten J, Fuller T, Lusis A, Horvath S
BMC Syst Biol
. 2008 Apr;
2:34.
PMID: 18412962
Background: Systems genetic studies have been used to identify genetic loci that affect transcript abundances and clinical traits such as body weight. The pairwise correlations between gene expression traits and/or...
5.
Fuller T, Ghazalpour A, Aten J, Drake T, Lusis A, Horvath S
Mamm Genome
. 2007 Aug;
18(6-7):463-72.
PMID: 17668265
Systems-oriented genetic approaches that incorporate gene expression and genotype data are valuable in the quest for genetic regulatory loci underlying complex traits. Gene coexpression network analysis lends itself to identification...