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Jason Dong

Explore the profile of Jason Dong including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 1091
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Recent Articles
1.
Li S, Wu Z, Tantray I, Li Y, Chen S, Dong J, et al.
Proc Natl Acad Sci U S A . 2020 Sep; 117(40):25104-25115. PMID: 32958650
Maintaining the fidelity of nascent peptide chain (NP) synthesis is essential for proteome integrity and cellular health. Ribosome-associated quality control (RQC) serves to resolve stalled translation, during which untemplated Ala/Thr...
2.
Wu Z, Tantray I, Lim J, Chen S, Li Y, Davis Z, et al.
Mol Cell . 2019 Aug; 75(4):835-848.e8. PMID: 31378462
Mitochondrial dysfunction and proteostasis failure frequently coexist as hallmarks of neurodegenerative disease. How these pathologies are related is not well understood. Here, we describe a phenomenon termed MISTERMINATE (mitochondrial-stress-induced translational...
3.
Wu Z, Wu A, Dong J, Sigears A, Lu B
Exp Gerontol . 2018 Sep; 113:10-17. PMID: 30248358
Recent studies suggest that moderate red wine consumption may confer several health benefits, including protection against heart disease, certain cancers and multiple age-related neurological diseases such as Alzheimer's disease. These...
4.
Kermany D, Goldbaum M, Cai W, Valentim C, Liang H, Baxter S, et al.
Cell . 2018 Feb; 172(5):1122-1131.e9. PMID: 29474911
The implementation of clinical-decision support algorithms for medical imaging faces challenges with reliability and interpretability. Here, we establish a diagnostic tool based on a deep-learning framework for the screening of...