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Jason D Peterson

Explore the profile of Jason D Peterson including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 491
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Recent Articles
1.
Al-Turkmani M, Godwin K, Peterson J, Tsongalis G
J Appl Lab Med . 2021 Feb; 3(2):178-184. PMID: 33636938
Background: Molecular tests have been increasingly used in the management of various cancers as more targeted therapies are becoming available as treatment options. The Idylla™ system is a fully integrated,...
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De Abreu F, Peterson J, Deharvengt S, Daber R, Sarsani V, Spotlow V, et al.
J Appl Lab Med . 2020 Jul; 2(2):138-149. PMID: 32630970
Background: Next-generation sequencing (NGS) assays are highly complex tests that can vary substantially in both their design and intended application. Despite their innumerous advantages, NGS assays present some unique challenges...
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Bernhardt E, Chamberlin M, Gorlov I, De Abreu F, Bloch K, Peterson J, et al.
Pract Lab Med . 2020 Jul; 21:e00174. PMID: 32613070
Matching of actionable tumor mutations with targeted therapy increases response rates and prolongs survival in lung cancer patients. Drug development and trials targeting genetic alterations are expanding rapidly. We describe...
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Kumar N, Tafe L, Higgins J, Peterson J, de Abreu F, Deharvengt S, et al.
Methods Inf Med . 2018 Apr; 57(1):63-73. PMID: 29621832
Objective: We aim to build an informatics methodology capable of identifying statistically significant associations between the clinical findings of non-small cell lung cancer (NSCLC) recorded in patient pathology reports and...
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Shajani-Yi Z, De Abreu F, Peterson J, Tsongalis G
Neoplasia . 2018 Feb; 20(3):256-262. PMID: 29454261
The tumor suppressor gene TP53 is the most frequently mutated gene in human cancer. It encodes p53, a DNA-binding transcription factor that regulates multiple genes involved in DNA repair, metabolism,...
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Miraflor A, De Abreu F, Peterson J, Turner S, Amos C, Tsongalis G, et al.
Exp Mol Pathol . 2017 Aug; 103(2):172-177. PMID: 28822769
Advanced stage malignant melanoma often responds poorly to therapy with low survival rates. New therapeutic approaches are based upon a growing understanding of the underlying molecular abnormalities. We demonstrate the...
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Hampel K, De Abreu F, Sidiropoulos N, Peterson J, Tsongalis G
Exp Mol Pathol . 2017 Feb; 102(2):215-218. PMID: 28192086
Targeted genomic profiling (TGP) using massively parallel DNA sequencing is becoming the standard methodology in clinical laboratories for detecting somatic variants in solid tumors. The variety of methodologies and sequencing...
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Gardner J, Peterson J, Turner S, Soares B, Lancor C, Dos Santos L, et al.
Am J Clin Pathol . 2016 Oct; 146(4):448-55. PMID: 27686171
Objectives: To describe three methods used to screen for frameshift mutations in exon 9 of the CALR gene. Methods: Genomic DNA from 47 patients was extracted from peripheral blood and...
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Tafe L, Pierce K, Peterson J, De Abreu F, Memoli V, Black C, et al.
Neoplasia . 2016 Sep; 18(9):577-83. PMID: 27659017
Detection of somatic mutations in non-small cell lung cancers (NSCLCs), especially adenocarcinomas, is important for directing patient care when targeted therapy is available. Here, we present our experience with genotyping...