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Jason Brenchley

Explore the profile of Jason Brenchley including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 653
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Recent Articles
1.
Sortino O, Phanuphak N, Schuetz A, Ortiz A, Chomchey N, Belkaid Y, et al.
Open Forum Infect Dis . 2020 Dec; 7(12):ofz367. PMID: 33324725
Background: Intestinal microbial dysbiosis is evident in chronic HIV-infected individuals and may underlie inflammation that persists even during antiretroviral therapy (ART). It remains unclear, however, how early after HIV infection...
2.
Sortino O, Phanuphak N, Schuetz A, Ortiz A, Chomchey N, Belkaid Y, et al.
Open Forum Infect Dis . 2020 Oct; 7(9):ofaa381. PMID: 33006329
[This corrects the article DOI: 10.1093/ofid/ofz367.].
3.
Tisza M, Pastrana D, Welch N, Stewart B, Peretti A, Starrett G, et al.
Elife . 2020 Feb; 9. PMID: 32014111
Although millions of distinct virus species likely exist, only approximately 9000 are catalogued in GenBank's RefSeq database. We selectively enriched for the genomes of circular DNA viruses in over 70...
4.
Klase Z, Yedavalli V, Houzet L, Perkins M, Maldarelli F, Brenchley J, et al.
PLoS Pathog . 2014 Mar; 10(3):e1003997. PMID: 24651404
A major barrier to the elimination of HIV-1 infection is the presence of a pool of long-lived, latently infected CD4+ memory T-cells. The search for treatments to re-activate latent HIV...
5.
Apetrei C, Gaufin T, Gautam R, Vinton C, Hirsch V, Lewis M, et al.
J Infect Dis . 2010 Oct; 202 Suppl 3:S371-6. PMID: 20887227
Patas monkeys were not reported to carry species‐specific simian immunodeficiency virus (SIV), but cross‐species transmission of SIVagm to patas monkeys occurred in the wild. We report that patas monkeys share...
6.
Cummins N, Jiang W, McGinty J, Bren G, Bosch R, Landay A, et al.
J Infect Dis . 2010 Jun; 202(3):386-91. PMID: 20565257
Casp8p41 is a protein fragment generated by cleavage of procaspase 8 by human immunodeficiency virus (HIV) protease. We measured Casp8p41 content in memory CD4 T cells and analyzed the association...
7.
Alter G, Brenchley J, Fellay J
IAVI Rep . 2010 Mar; 13(1):14-7. PMID: 20214278
No abstract available.
8.
Nies-Kraske E, Schacker T, Condoluci D, Orenstein J, Brenchley J, Fox C, et al.
J Infect Dis . 2009 May; 199(11):1648-56. PMID: 19432547
Most human immunodeficiency virus (HIV)-infected individuals experience increases in peripheral CD4(+) T cell counts with suppressive antiretroviral therapy (ART) that achieves plasma HIV RNA levels that are less than the...
9.
Kubo M, Nishimura Y, Shingai M, Lee W, Brenchley J, LaFont B, et al.
J Virol . 2009 May; 83(14):7099-108. PMID: 19420078
We investigated whether a 28-day course of potent antiretroviral therapy, initiated at a time point (48 h postinoculation) following simian immunodeficiency virus (SIV) inoculation when the acquisition of a viral...
10.
Burgers W, Riou C, Mlotshwa M, Maenetje P, de Assis Rosa D, Brenchley J, et al.
J Immunol . 2009 Apr; 182(8):4751-61. PMID: 19342652
Understanding early immunological events during HIV-1 infection that may set the course of disease progression is important for identifying correlates of viral control. This study explores the association of differentiation...