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Jason A Tye-Din

Explore the profile of Jason A Tye-Din including associated specialties, affiliations and a list of published articles. Areas
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Citations 1305
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Recent Articles
1.
Hardy M, Russell A, Henneken L, Tanner G, Bekes F, Brown I, et al.
Gut . 2025 Feb; PMID: 39961645
Background: Oat ingestion in coeliac disease (CD) is generally regarded as safe but can trigger enteropathy and T cells specific for oat avenin in the gut and blood of some...
2.
Daveson A, Stubbs R, Polasek T, Isola J, Anderson R, Tye-Din J, et al.
Lancet Gastroenterol Hepatol . 2024 Nov; 10(1):44-54. PMID: 39521016
Background: IMU-856 is an orally available and systemically acting small molecule modulator of sirtuin 6 (SIRT6), a protein that serves as a transcriptional regulator of bowel epithelium regeneration. We aimed...
3.
Adams D, Moleski S, Jossen J, Tye-Din J
Gastroenterology . 2024 Jul; 167(6):1245. PMID: 39038761
No abstract available.
4.
Thomson R, Oakey H, Haynes A, Craig M, Harrison L, Wentworth J, et al.
BMJ Open Diabetes Res Care . 2024 Jul; 12(4). PMID: 39013632
Introduction: The Environmental Determinants of Islet Autoimmunity (ENDIA) Study is an ongoing Australian prospective cohort study investigating how modifiable prenatal and early-life exposures drive the development of islet autoimmunity and...
5.
Tye-Din J
JGH Open . 2024 Jul; 8(7):e13107. PMID: 38957478
The traditional gut-centric view of coeliac disease is evolving as immune and genetic insights underscore the central importance of a systemic, T cell immune response to gluten in disease pathogenesis....
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Saitta D, Henneken L, Apputhurai P, Chen Yi Mei S, Tye-Din J
Dig Dis Sci . 2024 Apr; 69(7):2548-2557. PMID: 38683433
Introduction: Non-responsive coeliac disease (NRCD), where symptoms and enteropathy persist despite a prolonged gluten-free diet (GFD), is common. Refractory coeliac disease (RCD), characterised by malabsorption and extensive enteropathy, is rare...
8.
Silvester J, Elli L, Khosla C, Tye-Din J
Gastroenterology . 2024 Apr; 167(1):159-171. PMID: 38670279
Although many biomarkers have been proposed, and several are in widespread clinical use, there is no single readout or combination of readouts that correlates tightly with gluten exposure, disease activity,...
9.
Adams D, Moleski S, Jossen J, Tye-Din J
Gastroenterology . 2024 Apr; 167(1):51-63. PMID: 38636679
Views on the clinical presentation and symptomatology of celiac disease have evolved alongside advances in disease detection and understanding of disease pathogenesis. Although historically regarded as a pediatric illness characterized...
10.
Knowles S, Apputhurai P, Tye-Din J
Aliment Pharmacol Ther . 2024 Mar; 59(10):1260-1270. PMID: 38445780
Background: Brain fog is a subjective cognitive impairment commonly reported in coeliac disease. A standardised tool to define and assess it is an important unmet need. Aims: To develop a...