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Jaroslaw Szczyrba

Explore the profile of Jaroslaw Szczyrba including associated specialties, affiliations and a list of published articles. Areas
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Citations 432
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Recent Articles
1.
Szczyrba J, Jung V, Beitzinger M, Nolte E, Wach S, Hart M, et al.
Prostate Cancer . 2017 Feb; 2017:4893921. PMID: 28163933
Posttranscriptional gene regulation by microRNAs (miRNAs) contributes to the induction and maintenance of prostate carcinoma (PCa). To identify mRNAs enriched or removed from Ago2-containing RISC complexes, these complexes were immunoprecipitated...
2.
Szczyrba J, Niesen A, Wagner M, Wandernoth P, Aumuller G, Wennemuth G
J Biol Chem . 2016 Dec; 292(5):2021-2031. PMID: 28003366
The histogenesis of prostatic neuroendocrine cells is controversial: a stem cell hypothesis with a urogenital sinus-derived progeny of all prostatic epithelial cells is opposed by a dual origin hypothesis, favoring...
3.
Wandernoth P, Mannowetz N, Szczyrba J, Grannemann L, Wolf A, Becker H, et al.
J Biol Chem . 2015 Oct; 290(49):29202-16. PMID: 26487715
HCO3 (-) is a key factor in the regulation of sperm motility. High concentrations of HCO3 (-) in the female genital tract induce an increase in sperm beat frequency, which...
4.
Hart M, Nolte E, Wach S, Szczyrba J, Taubert H, Rau T, et al.
Mol Cancer Res . 2013 Dec; 12(2):250-63. PMID: 24337069
Unlabelled: MicroRNAs (miRNA) posttranscriptionally regulate gene expression and are important in tumorigenesis. Previous deep sequencing identified the miRNA profile of prostate carcinoma versus nonmalignant prostate tissue. Here, we generated miRNA...
5.
Hart M, Wach S, Nolte E, Szczyrba J, Menon R, Taubert H, et al.
FEBS J . 2013 Mar; 280(9):2105-16. PMID: 23480797
Prostate cancer is a leading cause of cancer mortality in men. One of the distinct characteristics of prostate cancer is over-expression of the ERG proto-oncogene. The TMPRSS2-ERG gene fusion, the...
6.
Szczyrba J, Nolte E, Hart M, Doll C, Wach S, Taubert H, et al.
Int J Cancer . 2012 Jul; 132(4):775-84. PMID: 22815235
In primary prostate cancer (PCa), a major cause of cancer-related death in men, the expression of various microRNAs (miRNAs) is deregulated. We previously detected several miRNAs, for example, miR-24 and...
7.
Szczyrba J, Nolte E, Wach S, Kremmer E, Stohr R, Hartmann A, et al.
Mol Cancer Res . 2011 May; 9(6):791-800. PMID: 21593139
Prostate carcinoma (CaP) is a leading cause of cancer-related death in men. We have previously determined the microRNA (miRNA) profile of primary CaP in comparison with nontumor prostate tissue. miRNAs...
8.
Wach S, Nolte E, Szczyrba J, Stohr R, Hartmann A, Orntoft T, et al.
Int J Cancer . 2011 Mar; 130(3):611-21. PMID: 21400514
MicroRNAs (miRNAs) are small RNA molecules that regulate gene expression via posttranscriptional inhibition of protein synthesis. They play a vital role in tumorigenesis. To characterize the diagnostic potential of miRNAs...
9.
Szczyrba J, Loprich E, Wach S, Jung V, Unteregger G, Barth S, et al.
Mol Cancer Res . 2010 Apr; 8(4):529-38. PMID: 20353999
Prostate cancer is a leading cause of tumor mortality. To characterize the underlying molecular mechanisms, we have compared the microRNA (miRNA) profile of primary prostate cancers and noncancer prostate tissues...