Jaroslaw Staszkiewicz
Overview
Explore the profile of Jaroslaw Staszkiewicz including associated specialties, affiliations and a list of published articles.
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19
Citations
187
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Recent Articles
1.
Singh P, Beyl R, Stephens J, Richard A, Boudreau A, Hebert R, et al.
Obesity (Silver Spring)
. 2024 Oct;
32(12):2264-2274.
PMID: 39462901
Objective: The objective of this study was to examine the changes in adipose tissue lipolytic capacity and insulin signaling in response to shortened sleep duration (SSD) in postmenopausal women. Methods:...
2.
Batdorf H, Lawes L, Cassagne G, Fontenot M, Harvey I, Richardson J, et al.
Diabetes Obes Metab
. 2024 Mar;
26(6):2158-2166.
PMID: 38433703
Aim: Type 1 diabetes results from autoimmune events influenced by environmental variables, including changes in diet. This study investigated how feeding refined versus unrefined (aka 'chow') diets affects the onset...
3.
Herion N, Kruger C, Staszkiewicz J, Kappen C, Salbaum J
Birth Defects Res
. 2018 Nov;
111(14):999-1012.
PMID: 30451383
Background: Impairments in cell migration during vertebrate gastrulation lead to structural birth defects, such as heart defects and neural tube defects. These defects are more frequent in progeny from diabetic...
4.
Floyd Z, Floyd E, Staszkiewicz J, Power R, Kilroy G, Kirk-Ballard H, et al.
Cell Reprogram
. 2015 Apr;
17(2):95-105.
PMID: 25826722
There is ample evidence that the ubiquitin-proteasome system is an important regulator of transcription and its activity is necessary for maintaining pluripotency and promoting cellular reprogramming. Moreover, proteasome activity contributes...
5.
Staszkiewicz J, Power R, Harkins L, Barnes C, Strickler K, Rim J, et al.
Cell Reprogram
. 2013 Sep;
15(5):397-404.
PMID: 24020699
Histone deacetylases (HDACs) catalyze deacetylation of histones that results in altered transcriptional activity. Inhibitors of HDACs have been shown to induce transcriptional changes that contribute positively to reprogramming somatic cells...
6.
Staszkiewicz J, Gimble J, Dietrich M, Gawronska-Kozak B
Stem Cells Dev
. 2011 Apr;
21(2):249-59.
PMID: 21510817
Stem Cell Antigen-1 (Sca-1) is a member of the lymphocyte-activated protein 6 family and has served as a marker for the identification of stem cells in various tissues, including fat...
7.
Rim J, Strickler K, Barnes C, Harkins L, Staszkiewicz J, Power R, et al.
Methods Mol Biol
. 2010 Nov;
702:299-316.
PMID: 21082411
Small molecules will need to be identified and/or developed that target protein classes limiting reprogramming efficiency. A specific class of proteins includes epigenetic regulators that silence, or minimize expression, of...
8.
Tang T, Zhang J, Yin J, Staszkiewicz J, Gawronska-Kozak B, Jung D, et al.
J Biol Chem
. 2009 Dec;
285(7):4637-44.
PMID: 20018865
To study the metabolic activity of NF-kappaB, we investigated phenotypes of two different mouse models with elevated NF-kappaB activities. The transcriptional activity of NF-kappaB is enhanced either by overexpression of...
9.
Staszkiewicz J, Frazier T, Rowan B, Bunnell B, Chiu E, Gimble J, et al.
Stem Cells Dev
. 2009 Apr;
19(1):83-92.
PMID: 19400629
Ear mesenchymal stem cells (EMSCs) represent a readily accessible population of stem-like cells that are adherent, clonogenic, and have the ability to self-renew. Previously, we have demonstrated that they can...
10.
Staszkiewicz J, Gimble J, Cain C, Dietrich M, Burk D, Kirk-Ballard H, et al.
Biochem Biophys Res Commun
. 2008 Dec;
378(3):539-44.
PMID: 19056354
This study has determined the natural frequency and localization of progenitor/stem cells within fat depots in situ based on their ability to retain DNA nucleotide label (BrdU). Neonate and mature...