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Jaroslav Icha

Explore the profile of Jaroslav Icha including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 616
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Recent Articles
1.
Rocha-Martins M, Nerli E, Kretzschmar J, Weigert M, Icha J, Myers E, et al.
Nature . 2023 Aug; 620(7974):615-624. PMID: 37558872
The concomitant occurrence of tissue growth and organization is a hallmark of organismal development. This often means that proliferating and differentiating cells are found at the same time in a...
2.
Czechowska K, Lannigan J, Wang L, Arcidiacono J, Ashhurst T, Barnard R, et al.
Cytometry A . 2019 Jun; 95(6):598-644. PMID: 31207046
No abstract available.
3.
Sahgal P, Alanko J, Icha J, Paatero I, Hamidi H, Arjonen A, et al.
J Cell Sci . 2019 May; 132(11). PMID: 31076515
β1-integrins mediate cell-matrix interactions and their trafficking is important in the dynamic regulation of cell adhesion, migration and malignant processes, including cancer cell invasion. Here, we employ an RNAi screen...
4.
Moreno-Layseca P, Icha J, Hamidi H, Ivaska J
Nat Cell Biol . 2019 Jan; 21(2):122-132. PMID: 30602723
Cell adhesion to the extracellular matrix is fundamental to metazoan multicellularity and is accomplished primarily through the integrin family of cell-surface receptors. Integrins are internalized and enter the endocytic-exocytic pathway...
5.
Daniel K, Icha J, Horenburg C, Muller D, Norden C, Mansfeld J
Nat Commun . 2018 Aug; 9(1):3297. PMID: 30120238
The conditional and reversible depletion of proteins by auxin-mediated degradation is a powerful tool to investigate protein functions in cells and whole organisms. However, its wider applications require fusing the...
6.
Icha J, Weber M, Waters J, Norden C
Bioessays . 2017 Jul; 39(8). PMID: 28749075
Phototoxicity frequently occurs during live fluorescence microscopy, and its consequences are often underestimated. Damage to cellular macromolecules upon excitation light illumination can impair sample physiology, and even lead to sample...
7.
Icha J, Kunath C, Rocha-Martins M, Norden C
J Cell Biol . 2016 Nov; 215(2):259-275. PMID: 27810916
The arrangement of neurons into distinct layers is critical for neuronal connectivity and function. During development, most neurons move from their birthplace to the appropriate layer, where they polarize. However,...
8.
Icha J, Schmied C, Sidhaye J, Tomancak P, Preibisch S, Norden C
J Vis Exp . 2016 May; (110):e53966. PMID: 27167079
Light sheet fluorescence microscopy (LSFM) is gaining more and more popularity as a method to image embryonic development. The main advantages of LSFM compared to confocal systems are its low...
9.
Taverna E, Mora-Bermudez F, Strzyz P, Florio M, Icha J, Haffner C, et al.
Sci Rep . 2016 Feb; 6:21206. PMID: 26879757
Apical radial glia (aRG), the stem cells in developing neocortex, are unique bipolar epithelial cells, extending an apical process to the ventricle and a basal process to the basal lamina....
10.
Hnilicova J, Hozeifi S, Duskova E, Icha J, Tomankova T, Stanek D
PLoS One . 2011 Feb; 6(2):e16727. PMID: 21311748
There is increasing evidence to suggest that splicing decisions are largely made when the nascent RNA is still associated with chromatin. Here we demonstrate that activity of histone deacetylases (HDACs)...