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Jarod Rollins

Explore the profile of Jarod Rollins including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 410
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Recent Articles
1.
Ma Z, Horrocks J, Mir D, Cox M, Ruzga M, Rollins J, et al.
Front Cell Dev Biol . 2024 Jan; 11:1263344. PMID: 38161330
The highly conserved integrated stress response (ISR) reduces and redirects mRNA translation in response to certain forms of stress and nutrient limitation. It is activated when kinases phosphorylate a key...
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Adamla F, Rollins J, Newsom M, Snow S, Schosserer M, Heissenberger C, et al.
Cell Physiol Biochem . 2019 Apr; 52(5):970-983. PMID: 30977983
Background/aims: Regulation of mRNA translation is central to protein homeostasis and is optimized for speed and accuracy. Spontaneous recoding events occur virtually at any codon but at very low frequency...
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Howard A, Rollins J, Snow S, Castor S, Rogers A
Aging Cell . 2016 Aug; 15(6):1027-1038. PMID: 27538368
Although certain methods of lowering and/or altering mRNA translation are associated with increased lifespan, the mechanisms underlying this effect remain largely unknown. We previously showed that the increased lifespan conferred...
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Sapra A, Anko M, Grishina I, Lorenz M, Pabis M, Poser I, et al.
Mol Cell . 2009 Apr; 34(2):179-90. PMID: 19394295
The SR proteins are a family of pre-mRNA splicing factors with additional roles in gene regulation. To investigate individual family members in vivo, we generated a comprehensive panel of stable...
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Korstanje R, Desai J, Lazar G, King B, Rollins J, Spurr M, et al.
Physiol Genomics . 2008 Sep; 35(3):296-304. PMID: 18796533
The vacuolated lens (vl) mouse mutant arose spontaneously on the C3H/HeSn background and exhibits neural tube defects (NTDs), congenital cataract, and occasionally a white belly spot. We previously reported that...
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Matteson P, Desai J, Korstanje R, Lazar G, Borsuk T, Rollins J, et al.
Proc Natl Acad Sci U S A . 2008 Feb; 105(6):2088-93. PMID: 18250320
The vacuolated lens (vl) mouse mutant causes congenital cataracts and neural tube defects (NTDs), with the NTDs being caused by abnormal neural fold apposition and fusion. Our positional cloning of...
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Stylianou I, Affourtit J, Shockley K, Wilpan R, Abdi F, Bhardwaj S, et al.
Genetics . 2008 Feb; 178(3):1795-805. PMID: 18245842
Previous quantitative trait locus (QTL) analysis of an intercross involving the inbred mouse strains NZB/BlNJ and SM/J revealed QTL for a variety of complex traits. Many QTL have large intervals...
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Chen Y, Rollins J, Paigen B, Wang X
Cell Metab . 2007 Sep; 6(3):164-79. PMID: 17767904
Atherosclerosis is a complex disease involving genetic and environmental risk factors, acting on their own or in synergy. Within the general population, polymorphisms within genes in lipid metabolism, inflammation, and...
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Rollins J, Chen Y, Paigen B, Wang X
Trends Cardiovasc Med . 2006 Sep; 16(7):220-34. PMID: 16980179
Many lines of evidence suggest that raising plasma high-density lipoprotein cholesterol (HDL-C) levels may inhibit, perhaps even reverse, atherosclerosis. Quantitative trait locus (QTL) analysis has been performed in both humans...