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Janneke P Ouwerkerk

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Citations 2405
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Recent Articles
1.
Bachmann R, Van Hul M, Baldin P, Leonard D, Delzenne N, Belzer C, et al.
Cells . 2022 Sep; 11(17). PMID: 36078075
Anastomotic leakage is a major complication following colorectal surgery leading to peritonitis, complications, and mortality. has shown beneficial effects on the gut barrier function. Whether reduces peritonitis and mortality during...
2.
Ouwerkerk J, Tytgat H, Elzinga J, Koehorst J, Van den Abbeele P, Henrissat B, et al.
Microorganisms . 2022 Aug; 10(8). PMID: 36014023
Akkermansia muciniphila is a champion of mucin degradation in the human gastrointestinal tract. Here, we report the isolation of six novel strains from healthy human donors and their genomic, proteomic...
3.
Geerlings S, Ouwerkerk J, Koehorst J, Ritari J, Aalvink S, Stecher B, et al.
BMC Microbiol . 2021 Oct; 21(1):298. PMID: 34715771
Background: Akkermansia muciniphila is a member of the human gut microbiota where it resides in the mucus layer and uses mucin as the sole carbon, nitrogen and energy source. A....
4.
Hanninen A, Toivonen R, Poysti S, Belzer C, Plovier H, Ouwerkerk J, et al.
Gut . 2017 Dec; 67(8):1445-1453. PMID: 29269438
Objective: Intestinal microbiota is implicated in the pathogenesis of autoimmune type 1 diabetes in humans and in non-obese diabetic (NOD) mice, but evidence on its causality and on the role...
5.
Ouwerkerk J, Koehorst J, Schaap P, Ritari J, Paulin L, Belzer C, et al.
Genome Announc . 2017 Jan; 5(1). PMID: 28057747
Akkermansia glycaniphila is a novel Akkermansia species that was isolated from the intestine of the reticulated python and shares the capacity to degrade mucin with the human strain Akkermansia muciniphila...
6.
Ouwerkerk J, van der Ark K, Davids M, Claassens N, Finestra T, de Vos W, et al.
Appl Environ Microbiol . 2016 Sep; 82(23):6983-6993. PMID: 27663027
colonizes the mucus layer of the gastrointestinal tract, where the organism can be exposed to the oxygen that diffuses from epithelial cells. To understand how is able to survive and...
7.
Ouwerkerk J, Aalvink S, Belzer C, de Vos W
Int J Syst Evol Microbiol . 2016 Aug; 66(11):4614-4620. PMID: 27499019
A Gram-stain-negative, non-motile, strictly anaerobic, oval-shaped, non-spore-forming bacterium (strain PytT) was isolated from reticulated python faeces. Strain PytT was capable of using mucin as sole carbon, energy and nitrogen source....
8.
Guzman Prieto A, Urbanus R, Zhang X, Bierschenk D, Koekman C, van Luit-Asbroek M, et al.
Sci Rep . 2015 Dec; 5:18255. PMID: 26675410
Enterococcus faecium is a commensal of the mammalian gastrointestinal tract, but is also found in non-enteric environments where it can grow between 10 °C and 45 °C. E. faecium has...
9.
Ouwerkerk J, de Vos W, Belzer C
Best Pract Res Clin Gastroenterol . 2013 Jun; 27(1):25-38. PMID: 23768550
The human gastrointestinal tract is colonised with a dense and diverse microbial community, that is an important player in human health and physiology. Close to the epithelial cells the mucosal...
10.
Everard A, Belzer C, Geurts L, Ouwerkerk J, Druart C, Bindels L, et al.
Proc Natl Acad Sci U S A . 2013 May; 110(22):9066-71. PMID: 23671105
Obesity and type 2 diabetes are characterized by altered gut microbiota, inflammation, and gut barrier disruption. Microbial composition and the mechanisms of interaction with the host that affect gut barrier...