Janne M Toivonen
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Explore the profile of Janne M Toivonen including associated specialties, affiliations and a list of published articles.
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28
Citations
2233
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Recent Articles
1.
Hernaiz A, Sanz A, Sentre S, Ranera B, Lopez-Perez O, Zaragoza P, et al.
Front Vet Sci
. 2022 Mar;
9:824677.
PMID: 35252421
Scrapie is a neurodegenerative disorder belonging to the group of transmissible spongiform encephalopathy (TSE). Scrapie occurs in sheep and goats, which are considered good natural animal models of these TSE....
2.
Lopez-Perez O, Sanz-Rubio D, Hernaiz A, Betancor M, Otero A, Castilla J, et al.
Int J Mol Sci
. 2021 Jul;
22(13).
PMID: 34201940
Diagnosis of transmissible spongiform encephalopathies (TSEs), or prion diseases, is based on the detection of proteinase K (PK)-resistant PrP in post-mortem tissues as indication of infection and disease. Since PrP...
3.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy
. 2021 Feb;
17(1):1-382.
PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...
4.
Bjedov I, Cocheme H, Foley A, Wieser D, Woodling N, Castillo-Quan J, et al.
PLoS Genet
. 2020 Nov;
16(11):e1009083.
PMID: 33253201
Increased cellular degradation by autophagy is a feature of many interventions that delay ageing. We report here that increased autophagy is necessary for reduced insulin-like signalling (IIS) to extend lifespan...
5.
Toivonen J, Sanz-Rubio D, Lopez-Perez O, Marin-Moreno A, Bolea R, Osta R, et al.
Biomolecules
. 2020 Jun;
10(6).
PMID: 32549330
MicroRNAs (miRNAs) may contribute to the development and pathology of many neurodegenerative diseases, including prion diseases. They are also promising biomarker candidates due to their stability in body fluids. We...
6.
Calvo A, Moreno L, Moreno L, Toivonen J, Manzano R, Molina N, et al.
Neural Regen Res
. 2019 Dec;
15(6):988-995.
PMID: 31823868
Among collagen members in the collagen superfamily, type XIX collagen has raised increasing interest in relation to its structural and biological roles. Type XIX collagen is a Fibril-Associated Collagen with...
7.
Moreno-Martinez L, de la Torre M, Toivonen J, Zaragoza P, Garcia-Redondo A, Calvo A, et al.
Front Immunol
. 2019 Apr;
10:801.
PMID: 31031774
There is growing evidence of the role of inflammation in Amyotrophic Lateral Sclerosis (ALS) during the last decade. Although the origin of ALS remains unknown, multiple potential inflammatory biomarkers have...
8.
Lopez-Perez O, Otero A, Filali H, Sanz-Rubio D, Toivonen J, Zaragoza P, et al.
Sci Rep
. 2019 Feb;
9(1):1911.
PMID: 30760781
Autophagy is a dynamic cellular mechanism involved in protein and organelle turnover through lysosomal degradation. Autophagy regulation modulates the pathologies associated with many neurodegenerative diseases. Using sheep naturally infected with...
9.
Rando A, de la Torre M, Martinez-Muriana A, Zaragoza P, Musaro A, Hernandez S, et al.
PLoS One
. 2019 Jan;
14(1):e0210752.
PMID: 30640943
Amyotrophic lateral sclerosis (ALS) is a lethal motor neuron disease with no cure. Currently there are only two ALS drugs approved by the FDA, both with a limited therapeutic effect....
10.
Rubio D, Lopez-Perez O, de Andres Pablo A, Bolea R, Osta R, Badiola J, et al.
J Gen Virol
. 2016 Dec;
98(2):305-310.
PMID: 27959774
Scrapie is a transmissible spongiform encephalopathy (TSE), or prion disease, of sheep and goats. As no simple diagnostic tests are yet available to detect TSEs in vivo, easily accessible biomarkers...