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Janine Murr

Explore the profile of Janine Murr including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Nguyen A, Mustafa A, Leydecker A, Halilovic M, Murr J, Butter F, et al.
Cell Commun Signal . 2024 Apr; 22(1):217. PMID: 38570831
As a major source of cellular serine and threonine phosphatase activity, protein phosphatase-2A (PP2A) modulates signaling pathways in health and disease. PP2A complexes consist of catalytic, scaffolding, and B-type subunits....
2.
Orben F, Lankes K, Schneeweis C, Hassan Z, Jakubowsky H, Krauss L, et al.
JCI Insight . 2022 Apr; 7(10). PMID: 35439169
Systemic therapies for pancreatic ductal adenocarcinoma (PDAC) remain unsatisfactory. Clinical prognosis is particularly poor for tumor subtypes with activating aberrations in the MYC pathway, creating an urgent need for novel...
3.
Nguyen A, Dzulko M, Murr J, Yen Y, Schneider G, Kramer O
Cells . 2021 Oct; 10(10). PMID: 34685500
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive disease with a dismal prognosis. Here, we show how an inhibition of de novo dNTP synthesis by the ribonucleotide reductase (RNR) inhibitor...