Janez Prezelj
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Explore the profile of Janez Prezelj including associated specialties, affiliations and a list of published articles.
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38
Citations
1142
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Recent Articles
1.
Bedene A, Mencej Bedrac S, Jese L, Marc J, Vrtacnik P, Prezelj J, et al.
Wien Klin Wochenschr
. 2016 Dec;
128(Suppl 7):519-526.
PMID: 27900532
Background: Osteoporosis is a prevalent skeletal disorder characterized by reduced bone mineral density and microarchitectural deterioration of bone tissue, resulting in bone fragility and low-trauma fractures. Imaging techniques are routinely...
2.
Mlakar V, Jurkovic Mlakar S, Zupan J, Komadina R, Prezelj J, Marc J
J Cell Mol Med
. 2015 Mar;
19(7):1520-9.
PMID: 25818344
Adrenergic stimulation is important for osteoclast differentiation and bone resorption. Previous research shows that this happens through β2-adrenergic receptor (AR), but there are conflicting evidence on presence and role of...
3.
Mencej-Bedrac S, Zupan J, Jurkovic Mlakar S, Zavratnik A, Prezelj J, Marc J
Drug Metabol Drug Interact
. 2014 Mar;
29(2):111-4.
PMID: 24615483
Background: Raloxifene is a selective estrogen receptor (ER) modulator (SERM) used for the treatment of osteoporosis. However, its efficacy and also its safety vary greatly among treated patients, and it...
4.
Zupan J, Pristovsek N, Mencej-Bedrac S, Komadina R, Prezelj J, Marc J
Clin Chem Lab Med
. 2012 Aug;
50(8):1379-85.
PMID: 22868802
Background: Osteoporosis is a skeletal disorder, characterized by low bone mass and microarchitectural deterioration of bone tissue, leading to increased risk of fracture. Recently, the role of age-related pro-inflammatory cytokines,...
5.
Liu C, Estrada K, Yerges-Armstrong L, Amin N, Evangelou E, Li G, et al.
J Bone Miner Res
. 2012 Jun;
27(10):2051-64.
PMID: 22692763
Sexual dimorphism in various bone phenotypes, including bone mineral density (BMD), is widely observed; however, the extent to which genes explain these sex differences is unclear. To identify variants with...
6.
Estrada K, Styrkarsdottir U, Evangelou E, Hsu Y, Duncan E, Ntzani E, et al.
Nat Genet
. 2012 Apr;
44(5):491-501.
PMID: 22504420
Bone mineral density (BMD) is the most widely used predictor of fracture risk. We performed the largest meta-analysis to date on lumbar spine and femoral neck BMD, including 17 genome-wide...
7.
Jurkovic Mlakar S, Prezelj J, Osredkar J, Marc J
Gerontology
. 2012 Feb;
58(3):238-48.
PMID: 22327174
Background: Much research suggests that oxidative stress is associated with osteoporosis development. Glutathione S-transferases mu3 (GSTM3) are an important group of detoxifying enzymes that eliminate oxidative stress-related products. Objectives: To...
8.
Jurkovic Mlakar S, Prezelj J, Marc J
Maturitas
. 2012 Jan;
71(2):180-7.
PMID: 22221655
Objectives: Osteoporosis (OP) is an age-related disease associated with increased production of reactive oxygen species (ROS) and a reduction in antioxidant defense system, such as low activity of glutathione S-transferase...
9.
Jurkovic Mlakar S, Osredkar J, Prezelj J, Marc J
Menopause
. 2011 Nov;
19(3):368-76.
PMID: 22089180
Objective: Oxidative stress participates in decreasing bone formation and stimulating bone resorption. Furthermore, antioxidant enzymes have been observed to have low protective activity in women with osteoporosis.The aim of the...
10.
Jurkovic Mlakar S, Osredkar J, Prezelj J, Marc J
Dis Markers
. 2011 Nov;
31(5):279-87.
PMID: 22048269
Oxidative stress is associated with osteoporosis. The glutathione S-transferases form the major detoxifying group of enzymes responsible for eliminating products of oxidative stress. We have therefore proposed GSTM1 and GSTT1...