Janet R Morrow
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Explore the profile of Janet R Morrow including associated specialties, affiliations and a list of published articles.
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82
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653
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Recent Articles
1.
Cineus R, Dissanayake A, Morrow J
Inorg Chem
. 2024 Dec;
63(51):24049-24053.
PMID: 39653610
The development of responsive MRI contrast agents to detect fluctuations in Zn(II) is a growing area of research. Here we describe a high-spin Fe(III) coordination complex, Fe(ADAPT), as one of...
2.
Dissanayake A, Spernyak J, Morrow J
Chem Commun (Camb)
. 2024 Oct;
60(84):12249-12252.
PMID: 39364604
The incorporation of multiple Fe(III) centers bridged by rigid ligands into a coordination cage represents a powerful approach for designing effective MRI contrast agents. In this context, an octahedral coordination...
3.
Sahoo P, Spernyak J, Turowski S, Morrow J
Bioconjug Chem
. 2024 Sep;
PMID: 39303010
A T MRI probe based on a self-assembled coordination cage with four iron(III) centers acts as a host for the hydrolysis product of the gold(I) anticancer drug, Au(PEt)Cl. H NMR...
4.
Raymond J, Chowdhury M, Crawley M, Morrow J
Chemistry
. 2024 Jun;
30(47):e202401638.
PMID: 38861702
Macrocyclic Co(II) complexes with appended amide-glycinate groups were prepared to develop paramagnetic Co(II) chemical exchange saturation transfer (CEST) agents of reduced overall charge. Complexes with reduced charge and lowered osmolarity...
5.
Kras E, Cineus R, Crawley M, Morrow J
Dalton Trans
. 2024 Feb;
53(9):4154-4164.
PMID: 38318938
High-spin Fe(III) complexes of 1,4,7-triazacyclononane (TACN) with mixed oxygen donor pendants including hydroxypropyl, phenolate or amide groups are prepared for study as T MRI probes. Complexes with two hydroxypropyl pendants...
6.
Cineus R, Abozeid S, Sokolow G, Spernyak J, Morrow J
Inorg Chem
. 2023 Sep;
62(40):16513-16522.
PMID: 37748050
Fe(III) complexes containing a triamine framework and phenolate or hydroxypyridine donors are characterized and studied as MRI probes. In contrast to most Fe(III) MRI probes of linear chelates reported to...
7.
Chowdhury M, Kras E, Turowski S, Spernyak J, Morrow J
Biomater Sci
. 2023 Jul;
11(17):5942-5954.
PMID: 37470467
Liposomes containing high-spin Fe(III) coordination complexes were prepared towards the production of MRI probes with improved relaxivity. The amphiphilic Fe(III) complexes were anchored into the liposome with two alkyl chains...
8.
Raymond J, Abozeid S, Sokolow G, Bond C, Yap C, Nazarenko A, et al.
Dalton Trans
. 2023 Jul;
52(28):9831-9839.
PMID: 37401800
Co(II) complexes of 1,4,7,10-tetraazacyclododecane (CYCLEN) or 1,4,8,11-tetraazacyclotetradecane (CYCLAM) with 2-hydroxypropyl or carbamoylmethyl (amide) pendants are studied with the goal of developing paramagnetic chemical exchange saturation transfer (paraCEST) agents. Single-crystal X-ray...
9.
Morrow J, Raymond J, Chowdhury M, Sahoo P
Inorg Chem
. 2022 Sep;
61(37):14487-14499.
PMID: 36067522
The presence of multiple oxidation and spin states of first-row transition-metal complexes facilitates the development of switchable MRI probes. Redox-responsive probes capitalize on a change in the magnetic properties of...
10.
Kras E, Snyder E, Sokolow G, Morrow J
Acc Chem Res
. 2022 Apr;
55(10):1435-1444.
PMID: 35482819
Contrast agents are used in approximately 40% of all magnetic resonance imaging (MRI) procedures to improve the quality of the images based on the distribution and dynamic clearance of the...