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Jane Mulligan

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Articles 19
Citations 163
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Recent Articles
1.
Trieu H, Phung Khanh L, Ming D, Ho Quang C, Phan T, Nguyen Van V, et al.
BMC Med . 2022 Apr; 20(1):109. PMID: 35387649
Background: Dengue shock syndrome (DSS) is one of the major clinical phenotypes of severe dengue. It is defined by significant plasma leak, leading to intravascular volume depletion and eventually cardiovascular...
2.
Leopold D, Phillips R, Shahi N, Gien J, Marwan A, Kinsella J, et al.
J Pediatr Surg . 2019 Nov; 55(1):39-44. PMID: 31679772
Introduction: Accurate, real-time technology is needed to predict which newborns with congenital diaphragmatic hernia (CDH) will require ECMO. The Compensatory Reserve Index (CRI) is a noninvasive monitoring technology that continuously...
3.
Metzger A, Mulligan J, Grudic G
Mil Med . 2018 Apr; 183(suppl_1):119-123. PMID: 29635594
Background: New tools for diagnosis, monitoring, and treatment of elevated intracranial pressure (ICP) or compromised cerebral perfusion pressure (CPP) are urgently needed to improve outcomes after brain injury. Previous success...
4.
Choi Y, Leopold D, Campbell K, Mulligan J, Grudic G, Moulton S
J Pediatr Surg . 2017 Dec; 53(2):241-246. PMID: 29217323
Introduction: Physiologic compromise in children with acute appendicitis has heretofore been difficult to measure. We hypothesized that the Compensatory Reserve Index (CRI), a novel adjunctive cardiovascular status indicator, would be...
5.
Moulton S, Mulligan J, Santoro M, Bui K, Grudic G, Macleod D
J Trauma Acute Care Surg . 2017 May; 83(1 Suppl 1):S104-S111. PMID: 28463939
Background: Humans are able to compensate for significant blood loss with little change in traditional vital signs, limiting early detection and intervention. We hypothesized that the Compensatory Reserve Index (CRI),...
6.
Moulton S, Mulligan J, Srikiatkhachorn A, Kalayanarooj S, Grudic G, Green S, et al.
J Med Case Rep . 2016 Aug; 10(1):233. PMID: 27553703
Background: Early recognition and treatment of circulatory volume loss is essential in the clinical management of dengue viral infection. We hypothesized that a novel computational algorithm, originally developed for noninvasive...
7.
Gagnon D, Schlader Z, Adams A, Rivas E, Mulligan J, Grudic G, et al.
Shock . 2016 May; 46(3 Suppl 1):74-82. PMID: 27183303
Compensatory reserve represents the proportion of physiological responses engaged to compensate for reductions in central blood volume before the onset of decompensation. We hypothesized that compensatory reserve would be reduced...
8.
Stewart C, Mulligan J, Grudic G, Talley M, Jurkovich G, Moulton S
Shock . 2016 May; 46(3 Suppl 1):61-7. PMID: 27172155
Introduction: Humans are able to compensate for significant blood loss with little change in traditional vital signs. We hypothesized that an algorithm, which recognizes compensatory changes in photoplethysmogram (PPG) waveforms,...
9.
Stewart C, Nawn C, Mulligan J, Grudic G, Moulton S, Convertino V
J Spec Oper Med . 2016 Apr; 16(1):6-13. PMID: 27045488
Background: Humans are able to compensate for significant loss of their circulating blood volume, allowing vital signs to remain relatively stable until compensatory mechanisms are overwhelmed. The authors present several...
10.
Hinojosa-Laborde C, Howard J, Mulligan J, Grudic G, Convertino V
Am J Physiol Regul Integr Comp Physiol . 2016 Apr; 310(11):R1154-9. PMID: 27030667
Compensatory reserve was measured in baboons (n = 13) during hemorrhage (Hem) and lower-body negative pressure (LBNP) using a machine-learning algorithm developed to estimate compensatory reserve by detecting reductions in...