Jana Haase
Overview
Explore the profile of Jana Haase including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
685
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Recent Articles
1.
Kalinichenko L, Kornhuber J, Sinning S, Haase J, Muller C
ACS Chem Neurosci
. 2024 Mar;
15(7):1298-1320.
PMID: 38499042
Serotonin (5-HT) is a vital modulatory neurotransmitter responsible for regulating most behaviors in the brain. An inefficient 5-HT synaptic function is often linked to various mental disorders. Primarily, membrane proteins...
2.
Kalinichenko L, Muhle C, Jia T, Anderheiden F, Datz M, Eberle A, et al.
Cereb Cortex
. 2022 Mar;
33(3):844-864.
PMID: 35296883
Alcohol use, abuse, and addiction, and resulting health hazards are highly sex-dependent with unknown mechanisms. Previously, strong links between the SMPD3 gene and its coded protein neutral sphingomyelinase 2 (NSM)...
3.
Kalinichenko L, Muhle C, Jia T, Anderheiden F, Datz M, Eberle A, et al.
Mol Psychiatry
. 2021 Sep;
26(12):7403-7416.
PMID: 34584229
Mental disorders are highly comorbid and occur together with physical diseases, which are often considered to arise from separate pathogenic pathways. We observed in alcohol-dependent patients increased serum activity of...
4.
Haase J, Jones A, Mc Veigh C, Brown E, Clarke G, Ahnert-Hilger G
J Neurochem
. 2021 Jul;
159(1):156-171.
PMID: 34309872
The regulation of the serotonin transporter (SERT) by guanine nucleotide-binding protein alpha (Gα) q was investigated using Gαq knockout mice. In the absence of Gαq, SERT-mediated uptake of 5-hydroxytryptamine (5HT)...
5.
Brown E, Mc Veigh C, Santos L, Gogarty M, Muller H, Elfving B, et al.
Neuropharmacology
. 2018 May;
137:211-220.
PMID: 29723540
The serotonin transporter (SERT) facilitates high affinity reuptake of 5-HT from the extracellular fluid and dysregulation of transporter function has been implicated in a range of mood disorders including depression....
6.
Haase J, Grudzinska-Goebel J, Muller H, Munster-Wandowski A, Chow E, Wynne K, et al.
ACS Chem Neurosci
. 2017 Apr;
8(5):1101-1116.
PMID: 28362488
The serotonin transporter (SERT) mediates Na-dependent high-affinity serotonin uptake and plays a key role in regulating extracellular serotonin concentration in the brain and periphery. To gain novel insight into SERT...
7.
Schwamborn R, Brown E, Haase J
J Neurochem
. 2016 Mar;
137(3):423-35.
PMID: 26924154
The serotonin transporter (SERT) is responsible for high-affinity serotonin (5-HT) uptake from extracellular fluid and is a prominent pharmacological target in the treatment of depression. In recent years, depression has...
8.
Haase J, Brown E
Pharmacol Ther
. 2014 Dec;
147:1-11.
PMID: 25444754
Monoamine, in particular serotonergic neurotransmission has long been recognized as an important factor in the aetiology of depression. The serotonin transporter (SERT) is the primary regulator of serotonin levels in...
9.
Malynn S, Campos-Torres A, Moynagh P, Haase J
Neurochem Res
. 2013 Jan;
38(4):694-704.
PMID: 23338678
Pro-inflammatory cytokines have been implicated in the precipitation of depression and related disorders, and the antidepressant sensitive serotonin transporter (SERT) may be a major target for immune regulation in these...
10.
Fjorback A, Muller H, Haase J, Raarup M, Wiborg O
Biochem Biophys Res Commun
. 2011 Feb;
406(2):165-70.
PMID: 21295544
The monoamine transporters for dopamine (DAT), norepinephrine (NET) and serotonin (SERT) facilitate the homeostatic balance of neurotransmitters in the synaptic cleft and thus, play a fundamental role in regulating neuronal...