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Jan Vrbsky

Explore the profile of Jan Vrbsky including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 506
Followers 0
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Recent Articles
1.
Cassani M, Niro F, Fernandes S, Pereira-Sousa D, Faes Morazzo S, Durikova H, et al.
Nano Lett . 2025 Jan; 25(7):2600-2609. PMID: 39772635
Bio-nano interactions have been extensively explored in nanomedicine to develop selective delivery strategies and reduce systemic toxicity. To enhance the delivery of nanocarriers to cancer cells and improve the therapeutic...
2.
Cassani M, Fernandes S, Oliver-De La Cruz J, Durikova H, Vrbsky J, Patocka M, et al.
Adv Sci (Weinh) . 2023 Nov; 11(2):e2302965. PMID: 37946710
Interactions between living cells and nanoparticles are extensively studied to enhance the delivery of therapeutics. Nanoparticles size, shape, stiffness, and surface charge are regarded as the main features able to...
3.
Masarykova N, Tkadlec E, Chlup Z, Vrbsky J, Brysova A, Cernochova P, et al.
BMC Oral Health . 2023 Sep; 23(1):637. PMID: 37670283
Background: Orthodontic treatment is associated with numerous adverse side effects, such as enamel discoloration, demineralization or even caries. The presence of microleakage between the enamel and the adhesive and between...
4.
Ergir E, Oliver-De La Cruz J, Fernandes S, Cassani M, Niro F, Pereira-Sousa D, et al.
Sci Rep . 2022 Oct; 12(1):17409. PMID: 36257968
Cardiovascular diseases remain the leading cause of death worldwide; hence there is an increasing focus on developing physiologically relevant in vitro cardiovascular tissue models suitable for studying personalized medicine and...
5.
Vrbsky J, Vinarsky V, Perestrelo A, Oliver-De La Cruz J, Martino F, Pompeiano A, et al.
Genomics . 2021 Sep; 114(1):474. PMID: 34544621
No abstract available.
6.
Vrbsky J, Vinarsky V, Perestrelo A, De La Cruz J, Martino F, Pompeiano A, et al.
Genomics . 2021 Mar; 113(3):1349-1365. PMID: 33713822
Yes-associated protein 1 (YAP1) is a transcriptional co-activator downstream of Hippo pathway. The pathway exerts crucial roles in organogenesis and its dysregulation is associated with the spreading of different cancer...
7.
Pagliari S, Vinarsky V, Martino F, Perestrelo A, De La Cruz J, Caluori G, et al.
Cell Death Differ . 2020 Oct; 28(4):1193-1207. PMID: 33116297
The tight regulation of cytoskeleton dynamics is required for a number of cellular processes, including migration, division and differentiation. YAP-TEAD respond to cell-cell interaction and to substrate mechanics and, among...
8.
Cassani M, Fernandes S, Vrbsky J, Ergir E, Cavalieri F, Forte G
Front Bioeng Biotechnol . 2020 May; 8:323. PMID: 32391340
The research for heart therapies is challenged by the limited intrinsic regenerative capacity of the adult heart. Moreover, it has been hampered by the poor results obtained by tissue engineering...
9.
Oliver-De La Cruz J, Nardone G, Vrbsky J, Pompeiano A, Perestrelo A, Capradossi F, et al.
Biomaterials . 2019 Mar; 205:64-80. PMID: 30904599
The mechanoregulated proteins YAP/TAZ are involved in the adipogenic/osteogenic switch of mesenchymal stem cells (MSCs). MSC fate decision can be unbalanced by controlling substrate mechanics, in turn altering the transmission...
10.
Jelinkova S, Fojtik P, Kohutova A, Vilotic A, Markova L, Pesl M, et al.
Cells . 2019 Jan; 8(1). PMID: 30650618
Recent data on Duchenne muscular dystrophy (DMD) show myocyte progenitor's involvement in the disease pathology often leading to the DMD patient's death. The molecular mechanism underlying stem cell impairment in...