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Jan Stepniak

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Articles 35
Citations 223
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Recent Articles
1.
Matusiak A, Stepniak J, Lewandowski K, Lewinski A, Karbownik-Lewinska M
Metabolites . 2025 Feb; 15(2). PMID: 39997750
Central hypothyroidism is characterized by either decreased TSH or, more commonly, normal TSH. This study aims to check whether this biochemical difference related to the severity of the pituitary disease,...
2.
Stepniak J, Karbownik-Lewinska M
Cells . 2024 Nov; 13(21. PMID: 39513876
17β-estradiol plays a crucial role in regulating cellular processes in both reproductive and non-reproductive tissues, including the thyroid gland. It modulates oxidative stress and contributes to sexual dimorphism in thyroid...
3.
Skoczynska A, Gladysz A, Stepniak J, Karbownik-Lewinska M
Nutrients . 2024 Sep; 16(17). PMID: 39275325
We present results on the potential protective antioxidant properties of indole-3-butyric acid. Indole-3-butyric acid is an indole derivative defined as an auxin and widely known as a plant growth regulator....
4.
Wojciechowska-Durczynska K, Stepniak J, Lewinski A, Karbownik-Lewinska M
J Clin Med . 2024 Sep; 13(17). PMID: 39274506
Fc receptor-like (FCRL) genes play a role in the immune system by encoding proteins that function as receptors on the surface of immune cells. The clinical significance of FCRL gene...
5.
Stepniak J, Karbownik-Lewinska M
Cancers (Basel) . 2024 May; 16(9). PMID: 38730600
Melatonin, primarily synthesized in the pineal gland, plays a crucial role in regulating circadian rhythms and possesses significant antioxidative properties. By neutralizing free radicals and reducing oxidative stress, melatonin emerges...
6.
Gladysz A, Stepniak J, Karbownik-Lewinska M
Antioxidants (Basel) . 2023 Sep; 12(9). PMID: 37759991
The thyroid gland is the primary site of sodium/iodide symporter (NIS), an intrinsic plasma membrane protein responsible for the active uptake of iodine, which is indispensable for thyroid hormone synthesis....
7.
Stepniak J, Kozirog E, Karbownik-Lewinska M
Toxics . 2023 Sep; 11(9). PMID: 37755756
It is well-known that thyroid diseases are more prevalent in women than in men. The contribution of sex hormones may explain such disparity. The aim of this study was to...
8.
Matusiak A, Stepniak J, Lewinski A, Karbownik-Lewinska M
Front Immunol . 2023 May; 14:1107334. PMID: 37122698
Background: Mannan-binding lectin (MBL) is a main component of the lectin pathway of the complement system. Although there are some studies showing links between endocrine and immune systems, the ones...
9.
Stepniak J, Krawczyk-Lipiec J, Lewinski A, Karbownik-Lewinska M
Biomedicines . 2022 Nov; 10(11). PMID: 36428458
Sorafenib and lenvatinib are multi-targeted tyrosine kinase inhibitors which are currently approved to treat advanced hepatocellular carcinoma, renal cell carcinoma and radioiodine-refractory differentiated thyroid carcinoma. However this treatment is often...
10.
Iwan P, Stepniak J, Karbownik-Lewinska M
Life (Basel) . 2022 Jul; 12(7). PMID: 35888192
In the original article [...].